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三级医疗中心接受内镜逆行胰胆管造影术患者的临床特征与结局

Clinical Profiles and Outcomes of Patients Undergoing Endoscopic Retrograde Cholangiopancreatography in a Tertiary Care Center.

作者信息

Joseph Deni, Muraleedharanpillai Ramu, Kolassery Sandesh, Sebastian Saji

机构信息

Department of Medical Gastroenterology, Government Medical College Kottayam, Kerala, IND.

出版信息

Cureus. 2024 Feb 27;16(2):e55065. doi: 10.7759/cureus.55065. eCollection 2024 Feb.

Abstract

Introduction Endoscopic retrograde cholangiopancreatography (ERCP) is a lifesaving therapeutic procedure that carries its own complexities and risks. Clinicians use ERCP as a therapeutic tool for the treatment of biliary stones, malignant obstruction, and acute cholangitis.  Aim In our study, we aimed to analyze the clinical profile and outcome of patients who underwent ERCP in the Department of Medical Gastroenterology from August 2021 to February 2023 at Government Medical College Kottayam in India. Materials and methods We conducted a retrospective study using data from patients who underwent ERCP in the Department of Medical Gastroenterology from August 2021 to February 2023 at Government Medical College Kottayam. We used a semi-structured questionnaire, pro forma, laboratory investigation reports, and SPSS Statistics software (IBM Corp., Armonk, NY) for our data analysis. We included all patients older than 18 years. Results In our study 65% of the patients were female. The primary indication for ERCP was common bile duct stones. Of the 216 attempted ERCP cases, we performed successful cannulation in 201 patients, a success rate of 93%. The cannulation time was less than five minutes in the majority of the cases and more than five minutes in 30% of the cases. The commonest type of ampulla in our study was Type One. In our study patients with chronic obstructive pulmonary disease had an increased risk of developing post-ERCP pancreatitis. The most common complication in our study was pancreatitis, which occurred in 29 cases (14%). Only three cases had moderate to severe pancreatitis requiring a prolonged hospital stay of more than three days. There was one fatality immediately following ERCP probably owing to sepsis-induced myocarditis. Of the 201 cases, 15 (7.5%) required precut sphincterotomy. Conclusion Analysis of data from patients who underwent ERCP in our department showed that the procedure is safe and effective in treating biliary disorders. The successful cannulation rate and complication rate with ERCP in our tertiary care center are at par with other published data.

摘要

引言

内镜逆行胰胆管造影术(ERCP)是一种挽救生命的治疗方法,但其本身也存在复杂性和风险。临床医生将ERCP用作治疗胆结石、恶性梗阻和急性胆管炎的治疗工具。

目的

在我们的研究中,我们旨在分析2021年8月至2023年2月期间在印度科塔亚姆政府医学院医学胃肠病学系接受ERCP治疗的患者的临床特征和治疗结果。

材料和方法

我们进行了一项回顾性研究,使用了2021年8月至2023年2月期间在科塔亚姆政府医学院医学胃肠病学系接受ERCP治疗的患者的数据。我们使用半结构化问卷、表格、实验室检查报告和SPSS统计软件(IBM公司,纽约州阿蒙克)进行数据分析。我们纳入了所有年龄超过18岁的患者。

结果

在我们的研究中,65%的患者为女性。ERCP的主要指征是胆总管结石。在216例尝试进行的ERCP病例中,我们成功插管201例,成功率为93%。大多数病例的插管时间少于5分钟,30%的病例插管时间超过5分钟。我们研究中最常见的壶腹类型是I型。在我们的研究中,慢性阻塞性肺疾病患者发生ERCP后胰腺炎的风险增加。我们研究中最常见的并发症是胰腺炎,发生在29例(14%)患者中。只有3例患者发生中度至重度胰腺炎,需要延长住院时间超过3天。有1例患者在ERCP后立即死亡,可能是由于败血症性心肌炎。在201例患者中,15例(7.5%)需要进行预切开括约肌切开术。

结论

对我们科室接受ERCP治疗的患者数据进行分析表明,该手术在治疗胆道疾病方面是安全有效的。我们三级医疗中心ERCP的成功插管率和并发症发生率与其他已发表的数据相当。

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