Laboratory of Molecular and Translational Human Infectious Disease Research, Center for Infectious Diseases, Department of Pathology and Genomic Medicine, Houston Methodist Research Institute and Houston Methodist Hospital, Houston, United States.
Departments of Pathology and Laboratory Medicine and Microbiology and Immunology, Weill Cornell Medical College, New York, United States.
Euro Surveill. 2024 Mar;29(13). doi: 10.2807/1560-7917.ES.2024.29.13.2400129.
Group A isolates of the recently described M1 clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1 variant responsible for almost all recent M1 infections in Iceland.
A 组最近描述的 M1 分支的分离株已经在几个欧洲国家和其他地方导致人类感染。对 M1 分离株的全基因组序列分析发现，苏格兰的一些分离株与 2022 年和 2023 年在冰岛引起严重感染的大多数分离株之间存在密切的基因组关系。系统进化分析强烈表明，来自苏格兰或与之相关的分离株是导致冰岛最近几乎所有 M1 感染的 M1 变异株的前体。
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