Kristoffersson K, Gröndahl H G, Bratthall D
J Dent Res. 1985 Jan;64(1):58-61. doi: 10.1177/00220345850640011101.
The relationship between the presence of Streptococcus mutans and caries on approximal tooth surfaces was studied in a group of 28 children who were 13 years old at baseline. 700 surfaces in the pre-molar and molar region were studied. Sampling of S. mutans was performed with a toothpick method at the beginning of the study and after one and two years. From bite-wing radiographs, the approximal surfaces were recorded as caries-free, decayed, or restored. Progression of lesions during the two years was also studied. More new caries lesions and progression caries lesions were found on surfaces positive for S. mutans than on surfaces without, and the more S. mutans, the more lesions, 52% of the surfaces with positive S. mutans findings at all three sampling occasions became carious or had caries in a progressive form. Among the surfaces with no detectable S. mutans, the corresponding figure was 8%. 80 out of the 530 surfaces diagnosed as intact at the start of the study became carious over the two-year period. 69 of these were S. mutans-positive at the first and/or second sampling.
在一组28名基线时年龄为13岁的儿童中，研究了变形链球菌的存在与邻面龋之间的关系。对700个前磨牙和磨牙区域的表面进行了研究。在研究开始时以及1年和2年后，采用牙签法对变形链球菌进行采样。从咬合翼片X光片中，将邻面记录为无龋、龋坏或已修复。还研究了两年内病变的进展情况。在变形链球菌检测呈阳性的表面上发现的新龋损病变和进展性龋损病变比在未检测到变形链球菌的表面上更多，变形链球菌数量越多，病变越多。在所有三次采样时变形链球菌检测结果为阳性的表面中，52%出现龋坏或呈进展性龋坏。在未检测到变形链球菌的表面中，相应比例为8%。在研究开始时被诊断为完好的530个表面中，有80个在两年期间出现龋坏。其中69个在第一次和/或第二次采样时变形链球菌检测呈阳性。
