Department of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu, China.
Department of Pharmacy, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China.
Orthop Surg. 2024 May;16(5):1127-1133. doi: 10.1111/os.14040. Epub 2024 Mar 31.
Residual varus after total knee arthroplasty (TKA) can affect functional outcomes, which may worsen in the presence of obesity. However, no studies were found to compare the outcomes of obese patients involving postoperative residual mild varus or neutral. The aim of this study was to compare postoperative complications and prosthesis survival, and functional outcomes for knees of obese patients with neutral or mild varus after TKA.
We retrospectively reviewed 188 consecutive obese patients (body mass index ≥30 kg/m) at our hospital who underwent TKA due to varus knee osteoarthritis from January 2010 to December 2015. The mechanical hip-knee-ankle axis angle was measured in all patients at admission and discharge. Knee functions were retrospectively assessed based on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Knee Society Knee Score (KS-KS), Knee Society Function Score (KS-FS), Forgotten Joint Score (FJS), and range of motion (ROM). Continuous data were compared between knees with neutral or mild varus alignment using analysis of Student's t test or variance or the Kruskal-Wallis test as appropriate. For multiple comparisons of outcomes, we used Bonferroni-Dunn method to adjust p-values. Categorical data were compared using the chi-squared test.
Of the 156 knees in 137 obese patients who completed follow-up for a mean of 8.32 ± 1.47 years, 97 knees were corrected from varus to neutral and 54 knees were kept in mild residual varus. Patients with mild varus knees had significantly WOMAC (8.25 ± 8.637 vs. 14.97 ± 14.193, p = 0.009) and better FJS (86.03 ± 15.607 vs. 70.22 ± 30.031, p = 0.002). The two types of knees did not differ significantly in KS-KS, KS-FS, or ROM. Although one patient with a neutral knee had to undergo revision surgery, there was no significant difference between two groups.
For obese patients with osteoarthritis, preservation of residual varus alignment after TKA can improve functional outcomes without compromising prosthesis survival.
全膝关节置换术(TKA)后残余的内翻会影响功能结果,而肥胖会使情况恶化。然而,没有研究比较过肥胖患者术后轻度内翻或中立位的结果。本研究旨在比较 TKA 后肥胖患者中立位或轻度内翻的膝关节术后并发症和假体存活率以及功能结果。
我们回顾性分析了 2010 年 1 月至 2015 年 12 月在我院因膝内翻骨关节炎接受 TKA 的 188 例连续肥胖患者(体重指数≥30kg/m)的临床资料。所有患者入院时和出院时均测量机械髋膝踝轴角度。根据 Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)评分、Knee Society Knee Score(KS-KS)、Knee Society Function Score(KS-FS)、Forgotten Joint Score(FJS)和活动范围(ROM)对膝关节功能进行回顾性评估。使用 Student's t 检验或方差分析比较中立位或轻度内翻位膝关节的连续数据,必要时采用 Kruskal-Wallis 检验。对于结果的多次比较,我们使用 Bonferroni-Dunn 方法调整 p 值。使用卡方检验比较分类数据。
在 137 例完成平均 8.32±1.47 年随访的肥胖患者中,156 例膝关节中 97 例从内翻矫正至中立位,54 例保持轻度残余内翻。轻度内翻组的 WOMAC(8.25±8.637 vs. 14.97±14.193,p=0.009)和 FJS(86.03±15.607 vs. 70.22±30.031,p=0.002)明显更好。两组在 KS-KS、KS-FS 或 ROM 方面无显著差异。虽然中立位膝关节中有 1 例患者需要进行翻修手术,但两组间无显著差异。
对于骨关节炎肥胖患者,TKA 后保留残余内翻对线可以改善功能结果,而不会影响假体存活率。