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微生物生物技术和遗传工程在医学中的作用是什么?

What is the role of microbial biotechnology and genetic engineering in medicine?

机构信息

Institute of Sustainable Processes, Valladolid, Spain.

Department of Chemical Engineering and Environmental Technology, School of Industrial Engineering, University of Valladolid, Valladolid, Spain.

出版信息

Microbiologyopen. 2024 Apr;13(2):e1406. doi: 10.1002/mbo3.1406.

Abstract

Microbial products are essential for developing various therapeutic agents, including antibiotics, anticancer drugs, vaccines, and therapeutic enzymes. Genetic engineering techniques, functional genomics, and synthetic biology unlock previously uncharacterized natural products. This review highlights major advances in microbial biotechnology, focusing on gene-based technologies for medical applications.

摘要

微生物产物是开发各种治疗剂的关键,包括抗生素、抗癌药物、疫苗和治疗性酶。遗传工程技术、功能基因组学和合成生物学揭示了以前未被描述的天然产物。本文重点介绍了基于基因的微生物生物技术在医学应用方面的主要进展,突出了微生物生物技术的主要进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ac1/10982607/e051604667d4/MBO3-13-e1406-g005.jpg

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