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132例新生儿及婴儿主动脉缩窄手术入路及预后的15年分析

15-Year Analysis of Surgical Approaches and Outcomes for Coarctation in 132 Neonates and Infants.

作者信息

Stukov Yuriy, Jacobs Jeffrey P, Sharaf Omar M, Peek Giles J, Pitkin Andrew D, Cruz Beltrán Susana C, Lopez-Colon Dalia, Nixon Connie S, Bleiweis Mark S

机构信息

Congenital Heart Center, University of Florida, 1600 Archer Road, Gainesville, FL, 32608, USA.

出版信息

Pediatr Cardiol. 2025 Jan;46(1):173-180. doi: 10.1007/s00246-023-03360-1. Epub 2024 Apr 1.

Abstract

A variety of surgical approaches exist to treat aortic coarctation in neonates and infants. Our institutional approach is designed to match the surgical approach to the individual anatomy of the patient. The objective of this study is to evaluate operative characteristics and outcomes of all neonates and infants who underwent surgical repair of coarctation of the aorta or hypoplastic aortic arch at University of Florida from 2006 to 2021, inclusive, either in isolation or with concomitant repair of atrial septal defect (ASD) and/or ventricular septal defect (VSD). A retrospective review was performed of 132 patients aged 0-1 year who underwent surgical repair of aortic coarctation or hypoplastic aortic arch between 2006 and 2021, inclusive, either in isolation or with concomitant repair of ASD and/or VSD. Patients were divided into two groups based on the surgical approach: Group 1 = Median Sternotomy and Group 2 = Left Lateral Thoracotomy. Continuous variables are presented as median (minimum-maximum); categorical variables are presented as N (%). The most common operative technique in Group 1 was end-to-side reconstruction with ligation of the aortic isthmus. The most common operative technique in Group 2 was extended end-to-end repair. Operative Mortality was one patient (1/132 = 0.76%). Transcatheter intervention for recurrent coarctation was performed in seven patients (7/132 = 5.3%). Surgical re-intervention for recurrent coarctation was performed in three patients (3/132 = 2.3%). From these data, one can conclude that a strategy of matching the surgical approach to the anatomy of neonates and infants who underwent surgical repair of aortic coarctation or hypoplastic aortic arch, either in isolation or with concomitant repair of ASD and/or VSD, is associated with less than 1% Operative Mortality and less than 3% recurrent coarctation requiring reoperation.

摘要

存在多种手术方法用于治疗新生儿和婴儿的主动脉缩窄。我们机构的手术方法旨在根据患者的个体解剖结构来匹配手术方式。本研究的目的是评估2006年至2021年(含)期间在佛罗里达大学接受主动脉缩窄或主动脉弓发育不全手术修复的所有新生儿和婴儿的手术特征及结果,这些手术包括单独手术或同时修复房间隔缺损(ASD)和/或室间隔缺损(VSD)。对132例年龄在0至1岁之间、在2006年至2021年(含)期间接受主动脉缩窄或主动脉弓发育不全手术修复的患者进行了回顾性研究,这些手术包括单独手术或同时修复ASD和/或VSD。根据手术方式将患者分为两组:第1组 = 正中胸骨切开术,第2组 = 左外侧开胸术。连续变量以中位数(最小值 - 最大值)表示;分类变量以N(%)表示。第1组最常见的手术技术是端侧重建并结扎主动脉峡部。第2组最常见的手术技术是扩大端端修复。手术死亡率为1例患者(1/132 = 0.76%)。7例患者(7/132 = 5.3%)因复发性缩窄接受了经导管介入治疗。3例患者(3/132 = 2.3%)因复发性缩窄接受了手术再次干预。从这些数据可以得出结论,对于接受主动脉缩窄或主动脉弓发育不全手术修复(单独手术或同时修复ASD和/或VSD)的新生儿和婴儿,将手术方式与解剖结构相匹配的策略,其手术死亡率低于1%,再次缩窄需要再次手术的发生率低于3%。

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