Roytman Gregory R, Jabbouri Sahir S, O'Marr Jamieson, Raghuram Akshay, Beitler Brian, Irshad Suhail, Fram Brianna R, Yoo Brad J, Leslie Michael P, Riedel Matthew D, Tommasini Steven M, Wiznia Daniel H
Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, USA.
Orthopaedics, Mount Sinai Hospital, New Haven, USA.
Cureus. 2024 Feb 28;16(2):e55136. doi: 10.7759/cureus.55136. eCollection 2024 Feb.
The selection of the most optimal fixation method for fractures of the distal femur, whether intramedullary nail (NL), lateral locking plate (PL), or nail/plate (NP) is not always clear. This study retrospectively evaluates surgical patients with distal femur fractures and introduces a pilot study using cluster analysis to identify the most optimal fracture fixation method for a given fracture type.
This is a retrospective cohort study of patients 18 years and older with an isolated distal femur fracture who presented to our Level-1 trauma center between January 1, 2012, and December 31, 2022, and obtained NL, PL, or NP implants. Patients with polytrauma and those without at least six months of follow-up were excluded. A chart review was used to obtain demographics, fracture classification, fixation method, and postoperative complications. A cluster analysis was performed. The following factors were used to determine a successful outcome: ambulatory status pre-injury and 6-12 months postoperatively, infection, non-union, mortality, and implant failure.
A total of 169 patients met inclusion criteria. No statistically significant association between the fracture classification and fixation type with overall outcome was found. However, patients treated with an NP (n = 14) had a success rate of 92.9% vs only a 68.1% success rate in those treated with a PL (n = 116) (p = 0.106). The most notable findings in the cluster analysis (15 total clusters) included transverse extraarticular fractures demonstrating 100% success if treated with NP (n = 6), 50% success with NL (n=2), and 78.57% success with PL fixation (n=14). NP constructs in complete articular fractures demonstrated success in 100% of patients (n = 5), whereas 77.78% of patients treated with NL (n = 9) and 61.36% of those treated with PL (n = 44).
Plate fixation was the predominant fixation method used for distal third femur fractures regardless of fracture classification. However, NP constructs trended towards improved success rates, especially in complete intraarticular and transverse extraarticular fractures, suggesting the potential benefit of additional fixation with these fractures. Cluster analysis provided a heuristic way of creating patient profiles in patients with distal third femur fractures. However, a larger cohort study is needed to corroborate these findings to ultimately develop a clinical decision-making tool that also accounts for patient specific characteristics.
对于股骨远端骨折,选择最佳的固定方法,无论是髓内钉(NL)、外侧锁定钢板(PL)还是钉/钢板(NP),并不总是明确的。本研究回顾性评估了股骨远端骨折的手术患者,并引入了一项初步研究,使用聚类分析来确定给定骨折类型的最佳骨折固定方法。
这是一项回顾性队列研究,研究对象为2012年1月1日至2022年12月31日期间在我们的一级创伤中心就诊的18岁及以上孤立性股骨远端骨折患者,这些患者接受了NL、PL或NP植入物治疗。排除多发伤患者以及随访时间不足六个月的患者。通过查阅病历获取人口统计学信息、骨折分类、固定方法和术后并发症。进行了聚类分析。以下因素用于确定成功的结果:受伤前和术后6 - 12个月的行走状态、感染、骨不连、死亡率和植入物失败。
共有169例患者符合纳入标准。未发现骨折分类和固定类型与总体结果之间存在统计学上的显著关联。然而,接受NP治疗的患者(n = 14)成功率为92.9%,而接受PL治疗的患者(n = 116)成功率仅为68.1%(p = 0.106)。聚类分析(共15个聚类)中最显著的发现包括:横行关节外骨折,若采用NP治疗成功率为100%(n = 6),采用NL治疗成功率为50%(n = 2),采用PL固定成功率为78.57%(n = 14)。完全关节内骨折采用NP固定的患者成功率为100%(n = 5),而采用NL治疗的患者成功率为77.78%(n = 9),采用PL治疗的患者成功率为61.36%(n = 44)。
无论骨折分类如何,钢板固定是股骨远端三分之一骨折最主要的固定方法。然而,NP固定的成功率有上升趋势,尤其是在完全关节内和横行关节外骨折中,这表明这些骨折采用额外固定可能有益。聚类分析为创建股骨远端三分之一骨折患者的概况提供了一种启发式方法。然而,需要更大规模的队列研究来证实这些发现,以最终开发一种临床决策工具,该工具还应考虑患者的具体特征。