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非典型纤维黄色瘤病例研究：临床表现与治疗

Case Study of Atypical Fibroxanthoma: Presentation and Management.

作者信息

Woodson Johnnie, Baha Alexander, Verma Nikita

机构信息

Dermatology, Chaparral Medical Group, Rancho Cucamonga, USA.

出版信息

Cureus. 2024 Feb 27;16(2):e55094. doi: 10.7759/cureus.55094. eCollection 2024 Feb.

DOI:10.7759/cureus.55094
PMID:38558602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10978462/
Abstract

Atypical fibroxanthoma (AFX) is a rare spindle cell proliferation arising from significant sun exposure. AFX often appears as a red papule, typically found in the head and neck region of elderly patients. Since there is no specificity in immunohistology, various stains differentiate AFX from other skin cancers. The stains include cluster of differentiation 68 (CD68), cluster of differentiation 163 (CD163), vimentin, cytokeratin epithelial (CKAE), and melanin. While local recurrence is common, AFX rarely metastasizes. Thus, the treatment options are complete surgical excision or micrographically oriented histographic surgery.

摘要

非典型纤维黄色瘤（AFX）是一种因大量日晒引起的罕见梭形细胞增殖性病变。AFX常表现为红色丘疹，多见于老年患者的头颈部。由于免疫组织化学检查无特异性，需用多种染色方法将AFX与其他皮肤癌区分开来。这些染色包括分化簇68（CD68）、分化簇163（CD163）、波形蛋白、细胞角蛋白上皮（CKAE）和黑色素。虽然局部复发很常见，但AFX很少发生转移。因此，治疗方法是完整手术切除或显微定向组织学手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/752709b313ba/cureus-0016-00000055094-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/94d32a1cfdc1/cureus-0016-00000055094-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/ef0585e61fc8/cureus-0016-00000055094-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/5db63fdca083/cureus-0016-00000055094-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/91e6cdd14d5a/cureus-0016-00000055094-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/309619357cc5/cureus-0016-00000055094-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/e8f9fcad1904/cureus-0016-00000055094-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/360e6a3344bc/cureus-0016-00000055094-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/752709b313ba/cureus-0016-00000055094-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/94d32a1cfdc1/cureus-0016-00000055094-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/ef0585e61fc8/cureus-0016-00000055094-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/5db63fdca083/cureus-0016-00000055094-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/91e6cdd14d5a/cureus-0016-00000055094-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/309619357cc5/cureus-0016-00000055094-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/e8f9fcad1904/cureus-0016-00000055094-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/360e6a3344bc/cureus-0016-00000055094-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e29a/10978462/752709b313ba/cureus-0016-00000055094-i08.jpg

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本文引用的文献

1
Atypical Fibroxanthoma: Outcomes from a Large Single Institution Series.非典型纤维黄色瘤：一项大型单机构系列研究的结果。
Cancer Control. 2023 Jan-Dec;30:10732748231155699. doi: 10.1177/10732748231155699.
2
Atypical Fibroxanthoma Within a Melanoma: A Case Report.黑色素瘤内的非典型纤维黄色瘤：病例报告
Cureus. 2021 Dec 15;13(12):e20426. doi: 10.7759/cureus.20426. eCollection 2021 Dec.
3
Chemical Peels in Skin Cancer: A Review.皮肤癌中的化学剥脱术：综述
J Clin Aesthet Dermatol. 2020 Feb;13(2):53-57. Epub 2020 Feb 1.
4
Two friends with eroded nodules on the ears: atypical fibroxanthoma case report.两位耳部出现糜烂性结节的朋友：非典型纤维黄色瘤病例报告。
An Bras Dermatol. 2015 Jul-Aug;90(4):577-9. doi: 10.1590/abd1806-4841.20153313.
5
Atypical fibroxanthoma of the cheek-case report with dermatoscopy and dermatopathology.颊部非典型纤维黄色瘤——结合皮肤镜与组织病理学的病例报告。
Dermatol Pract Concept. 2014 Apr 30;4(2):77-80. doi: 10.5826/dpc.0402a16. eCollection 2014 Apr.