Pesapane Filippo, Nazzaro Gianluca, Lunardon Luisa, Coggi Antonella, Gianotti Raffaele
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milano, IT.
An Bras Dermatol. 2015 Jul-Aug;90(4):577-9. doi: 10.1590/abd1806-4841.20153313.
Atypical fibroxanthoma is an uncommon mesenchymal tumor that manifests clinically as a reddish papule or nodule in sun-exposed areas of the body. The clinical presentation is not specific and histology and immunohistochemistry are both necessary for a correct diagnosis. Surgery is the gold standard of therapy. Recurrence and metastasis should be excluded with a follow-up at 6 months, since this tumor should nowadays be considered a medium-grade neoplasm, rather than low-grade as previously believed. We report the case of two friends who came to our hospital during the same period, complaining of very similar lesions. After biopsy and immunohistochemical examination, a diagnosis of atypical fibroxanthoma in both cases was formulated.
非典型纤维黄色瘤是一种罕见的间叶组织肿瘤，临床上表现为身体暴露于阳光下部位的红色丘疹或结节。临床表现不具有特异性，正确诊断需要组织学和免疫组织化学检查。手术是治疗的金标准。应在6个月时进行随访以排除复发和转移，因为如今该肿瘤应被视为中度恶性肿瘤，而非如之前所认为的低度恶性肿瘤。我们报告了两名同期前来我院就诊的朋友的病例，他们都抱怨有非常相似的病变。经过活检和免疫组织化学检查，两例均诊断为非典型纤维黄色瘤。
