Nanda Siddhartha, Meher Papuji, M Rath Swaroopa, Gupta Rakesh Kumar, Galeti Revathi
Department of Radiation Oncology, AIIMS Raipur, Raipur, Chattisgarh India.
Department of Pathology and Lab Medicine, AIIMS Raipur, Raipur, Chattisgarh India.
Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):2134-2136. doi: 10.1007/s12070-023-04464-z. Epub 2023 Dec 28.
Giant Cell Tumors of the skull are rare and mostly occur in the middle cranial fossa. Radiological investigations serve as adjunct modalities; however, histopathological confirmation is mandatory. Ten to forty% of GCTs may be recurrent. Complete surgical resection is the treatment of choice, however, partial resection with adjuvant radiotherapy can serve as a secondary alternative. Recurrent cases require post-op radiotherapy. Here, we describe a case of recurrent giant cell tumor of sphenoid bone in a young male, who underwent surgical resection twice, after which he was advised adjuvant radiotherapy and denosumab. The patient did not take radiotherapy.
颅骨巨细胞瘤罕见,多发生于中颅窝。放射学检查作为辅助手段;然而,组织病理学确诊是必需的。10%至40%的巨细胞瘤可能复发。手术完全切除是首选治疗方法,不过,辅助放疗的部分切除可作为次要选择。复发病例需要术后放疗。在此,我们描述一例年轻男性蝶骨复发性巨细胞瘤病例,该患者接受了两次手术切除,术后建议进行辅助放疗和使用地诺单抗。患者未接受放疗。