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蝶骨复发性巨细胞瘤:一项罕见发现。

Recurrent Giant Cell Tumor of Sphenoid Bone: A Rare Finding.

作者信息

Nanda Siddhartha, Meher Papuji, M Rath Swaroopa, Gupta Rakesh Kumar, Galeti Revathi

机构信息

Department of Radiation Oncology, AIIMS Raipur, Raipur, Chattisgarh India.

Department of Pathology and Lab Medicine, AIIMS Raipur, Raipur, Chattisgarh India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):2134-2136. doi: 10.1007/s12070-023-04464-z. Epub 2023 Dec 28.

Abstract

Giant Cell Tumors of the skull are rare and mostly occur in the middle cranial fossa. Radiological investigations serve as adjunct modalities; however, histopathological confirmation is mandatory. Ten to forty% of GCTs may be recurrent. Complete surgical resection is the treatment of choice, however, partial resection with adjuvant radiotherapy can serve as a secondary alternative. Recurrent cases require post-op radiotherapy. Here, we describe a case of recurrent giant cell tumor of sphenoid bone in a young male, who underwent surgical resection twice, after which he was advised adjuvant radiotherapy and denosumab. The patient did not take radiotherapy.

摘要

颅骨巨细胞瘤罕见,多发生于中颅窝。放射学检查作为辅助手段;然而,组织病理学确诊是必需的。10%至40%的巨细胞瘤可能复发。手术完全切除是首选治疗方法,不过,辅助放疗的部分切除可作为次要选择。复发病例需要术后放疗。在此,我们描述一例年轻男性蝶骨复发性巨细胞瘤病例,该患者接受了两次手术切除,术后建议进行辅助放疗和使用地诺单抗。患者未接受放疗。

相似文献

1
Recurrent Giant Cell Tumor of Sphenoid Bone: A Rare Finding.蝶骨复发性巨细胞瘤:一项罕见发现。
Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):2134-2136. doi: 10.1007/s12070-023-04464-z. Epub 2023 Dec 28.

本文引用的文献

1
Denosumab treatment for giant-cell tumor of bone: a systematic review of the literature.地舒单抗治疗骨巨细胞瘤:文献系统评价。
Arch Orthop Trauma Surg. 2019 Oct;139(10):1339-1349. doi: 10.1007/s00402-019-03167-x. Epub 2019 Mar 15.
3
Giant cell tumour of bone in the denosumab era.地诺单抗时代的骨巨细胞瘤
Eur J Cancer. 2017 May;77:75-83. doi: 10.1016/j.ejca.2017.02.021. Epub 2017 Mar 30.
5
A locally invasive giant cell tumor of the skull base: case report.一例颅底局部侵袭性巨细胞瘤:病例报告
J Neurol Surg Rep. 2014 Aug;75(1):e175-9. doi: 10.1055/s-0034-1378153. Epub 2014 Jun 24.
6
Giant-cell tumors of the temporal bone: management strategies.颞骨巨细胞瘤:治疗策略
Skull Base. 2009 Jul;19(4):291-301. doi: 10.1055/s-0028-1115324.

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