Faizal Bini, Latheef Binshy, Kartha Niveditha
Department of ENT, Amrita institute of Medical Sciences, Amrita Vishwa Vidyapeetham University, Kochi, India.
Department of Biostatistics, Amrita institute of Medical Sciences, Amrita Vishwa Vidyapeetham University, Kochi, India.
Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):1682-1689. doi: 10.1007/s12070-023-04384-y. Epub 2023 Dec 5.
Objective Tympanometry is widely used for diagnosing Eustachian tube dysfunction (ETD). However, in clinical practice, it is not uncommon to come across patients with symptoms of ETD with a normal tympanogram. Dynamic slow motion video endoscopy (DSMVE) of Eustachian tube (ET) and Eustachian tube dysfunction questionnaire-7 (ETDQ-7) are other tools to diagnose ETD. Primary aim of the study was to compare DSMVE and tympanometry in diagnosing ETD. Secondary objective was to find an association between DSMVE and ETDQ-7. It was a prospective diagnostic validity study in the department of Otorhinolaryngology at a tertiary care centre. Patients with symptoms suggestive of ETD with intact tympanic membrane (TM) and aged above 12 years were evaluated. The study duration was 17 months. The parameters assessed were tympanic membrane(TM) retraction by otoscopy, DSMVE, tympanometry and ETDQ-7 questionnaire. To test the significance of association and difference between tympanogram and nasopharyngoscopy, Chi-Square t test and McNemar's tests were applied. Out of 107 ears, DSMVE, tympanometry, ETDQ- 7 and otoscopy detected ETD in 51, 31,70 and 57 ears respectively. DSMVE and tympanometry together detected ETD in 29 ears and did not detect in 54 ears. Both these diagnostic methods were not comparable statistically (moderate agreement- Kappa value- 0.542). Comparison of DSMVE with ETDQ-7 was statistically significant (-value- 0.004). Video nasopharyngoscopy cannot be a stand- alone diagnostic aid for ETD. ETDQ-7 questionnaire showed higher concordance with nasopharyngoscopy than tympanometry. Diagnostic accuracy was more when all four parameters were assessed together.
目的 鼓室导抗图广泛用于诊断咽鼓管功能障碍(ETD)。然而,在临床实践中,鼓膜图正常但有ETD症状的患者并不少见。咽鼓管动态慢动作视频内镜检查(DSMVE)和咽鼓管功能障碍问卷-7(ETDQ-7)是诊断ETD的其他工具。本研究的主要目的是比较DSMVE和鼓室导抗图在诊断ETD方面的差异。次要目的是找出DSMVE与ETDQ-7之间的关联。这是一项在三级医疗中心耳鼻喉科进行的前瞻性诊断效度研究。对鼓膜完整且年龄在12岁以上、有ETD症状的患者进行评估。研究持续时间为17个月。评估的参数包括耳镜检查发现的鼓膜(TM)内陷、DSMVE、鼓室导抗图和ETDQ-7问卷。为检验鼓室导抗图与鼻咽喉镜检查之间关联和差异的显著性,应用了卡方t检验和麦克尼马尔检验。在107只耳朵中,DSMVE、鼓室导抗图、ETDQ-7和耳镜检查分别在51只、31只、70只和57只耳朵中检测到ETD。DSMVE和鼓室导抗图共同在29只耳朵中检测到ETD,在54只耳朵中未检测到。这两种诊断方法在统计学上无可比性(中度一致性——卡方值——0.542)。DSMVE与ETDQ-7的比较具有统计学显著性(P值——0.004)。视频鼻咽喉镜检查不能作为ETD的独立诊断辅助手段。ETDQ-7问卷与鼻咽喉镜检查的一致性高于鼓室导抗图。当同时评估所有四个参数时,诊断准确性更高。