Departments of General Surgery, King Fahd University Hospital, Dammam, Saudi Arabia. College of Medicine, Imam Abdulrahamn Bin Faisal University, Dammam, Saudi Arabia.
Departments of Pathology, King Fahd University Hospital, Dammam, Saudi Arabia College of Medicine, Imam Abdulrahamn Bin Faisal University, Dammam, Saudi Arabia.
Med Arch. 2024;78(2):170-173. doi: 10.5455/medarh.2024.78.170-173.
Juvenile papillomatosis (JP) of the breast is a rare and benign proliferative disorder affecting young women. The affected patients tend to have an increased risk of breast cancer development during follow-up.
This article aims to highlight a rare entity of breast disease, that harbor risk of breast cancer.
Here, we present 2 cases of JP in young females; the first case is a 13 year-old presented with spontaneous nipple discharge, while the other patient is a 24 year-old presented with a right breast lump. Both patients had a total excision of the breast lesions, revealing JP at histology. Discussion: Juvenile Papillomatosis is considered a clinicopathological entity and is usually misdiagnosed as fibroadenoma clinically and radiologically, which requires histological correlation. The histologic findings are well-defined (hyperplasia, papillomatosis, and multiple cysts with foamy histiocytes).The controversy in management between surgery and observation is because of insufficient knowledge about the direct relationship between JP and subsequent cancer.
Considering the risk of developing breast cancer in JP, enrolling patients and their families in a close follow-up and surveillance program is crucial.
乳腺幼年性乳头状瘤病（JP）是一种罕见的良性增生性疾病，影响年轻女性。受影响的患者在随访期间乳腺癌发展的风险增加。
本文旨在强调一种具有乳腺癌风险的罕见乳腺疾病实体。
在这里，我们介绍了 2 例年轻女性的 JP 病例；第 1 例是 13 岁的患者，表现为自发性乳头溢液，另 1 例是 24 岁的患者，表现为右侧乳腺肿块。两名患者均行乳腺病变全切除术，组织学显示 JP。
幼年性乳头状瘤病被认为是一种临床病理实体，临床上和影像学上通常被误诊为纤维腺瘤，这需要组织学相关性。组织学表现明确（增生、乳头状瘤和多发性伴有泡沫状组织细胞的囊肿）。手术与观察之间的管理争议是因为对 JP 与随后癌症之间的直接关系了解不足。
考虑到 JP 发展为乳腺癌的风险，让患者及其家属参与密切随访和监测计划至关重要。
