Ametov A S, Kasatkin Iu N, Mit'kov V V, Gur'eva I V
Med Radiol (Mosk). 1985 Mar;30(3):39-41.
The concentration of a new tumor marker CA-19-9 was determined in the blood serum of 51 patients with different diseases and in 38 healthy persons. In 95% of the examined persons, the concentration of CA-19-9 in the blood serum did not exceed 15 Units/ml in health. In the patients with benign focal and diffuse liver diseases and in the patients with rectal cancer without metastases to the liver, the level and frequency of the elevated CA-19-9 content in the blood serum did not practically differ from those in health. In primary and metastatic liver cancer, the CA-19-9 content was considerably elevated in all the patients. The combination of the CA-19-9 and CEA tests did not add to the efficacy of differential diagnosis between benign and malignant liver lesions.
在51例患有不同疾病的患者以及38名健康人的血清中测定了一种新的肿瘤标志物CA - 19 - 9的浓度。在95%的受检者中,健康状态下血清中CA - 19 - 9的浓度不超过15单位/毫升。患有良性局灶性和弥漫性肝病的患者以及无肝转移的直肠癌患者,血清中CA - 19 - 9含量升高的水平和频率与健康人相比实际上并无差异。在原发性肝癌和转移性肝癌患者中,所有患者的CA - 19 - 9含量均显著升高。CA - 19 - 9和CEA检测联合使用并未提高肝良性和恶性病变鉴别诊断的效能。