Zhu Xia, Wu Ke, Anderson Stephan W, Zhang Xin
Department of Mechanical Engineering, Boston University, Boston, MA, 02215, USA.
Photonics Center, Boston University, Boston, MA, 02215, USA.
Adv Mater. 2024 Aug;36(31):e2313692. doi: 10.1002/adma.202313692. Epub 2024 Apr 12.
Recent advancements in metamaterials have yielded the possibility of a wireless solution to improve signal-to-noise ratio (SNR) in magnetic resonance imaging (MRI). Unlike traditional closely packed local coil arrays with rigid designs and numerous components, these lightweight, cost-effective metamaterials eliminate the need for radio frequency cabling, baluns, adapters, and interfaces. However, their clinical adoption is limited by their low sensitivity, bulky physical footprint, and limited, specific use cases. Herein, a wearable metamaterial developed using commercially available coaxial cable, designed for a 3.0 T MRI system is introduced. This metamaterial inherits the coaxially-shielded structure of its constituent cable, confining the electric field within and mitigating coupling to its surroundings. This ensures safer clinical adoption, lower signal loss, and resistance to frequency shifts. Weighing only 50 g, the metamaterial maximizes its sensitivity by conforming to the anatomical region of interest. MRI images acquired using this metamaterial with various pulse sequences achieve an SNR comparable or even surpass that of a state-of-the-art 16-channel knee coil. This work introduces a novel paradigm for constructing metamaterials in the MRI environment, paving the way for the development of next-generation wireless MRI technology.
超材料的最新进展带来了一种无线解决方案的可能性,以提高磁共振成像(MRI)中的信噪比(SNR)。与传统的紧密排列的具有刚性设计和众多组件的局部线圈阵列不同,这些轻质、经济高效的超材料无需射频电缆、巴伦、适配器和接口。然而,它们在临床上的应用受到其低灵敏度、庞大的物理尺寸和有限的特定用例的限制。在此,介绍一种使用商用同轴电缆开发的、专为3.0 T MRI系统设计的可穿戴超材料。这种超材料继承了其组成电缆的同轴屏蔽结构,将电场限制在内部并减轻与周围环境的耦合。这确保了更安全的临床应用、更低的信号损失以及对频率偏移的抗性。该超材料仅重50克,通过贴合感兴趣的解剖区域来最大化其灵敏度。使用这种超材料通过各种脉冲序列采集的MRI图像实现的信噪比与最先进的16通道膝关节线圈相当甚至更高。这项工作引入了一种在MRI环境中构建超材料的新范式,为下一代无线MRI技术的发展铺平了道路。