Nowotny H, Lutz D, Krieger O, Lambrou M, Bettelheim P
Wien Klin Wochenschr. 1985 Feb 1;97(3):153-61.
Karyotype analysis using the Tri-staining-technique (Chromomycin A3/Distamycin A/DAPI) and subsequent DAPI/AMD staining (Schweizer, 1981) was performed on the bone marrow and peripheral blood of three patients with "Burkitt-like" acute lymphatic leukaemia (FAB: L3). In two patients we found the specific translocation t(8;22). One patient displayed in addition a structural abnormality of chromosome 9, visualized with C-banding using the DA/DAPI stain, and in two patients we found specific abnormalities of chromosome 1. Several patterns of the abnormal chromosome 1 revealed an intercalated DA/DAPI positive C-band in the elongated long arm.
使用三色染色技术(嗜铬霉素A3/双脒苯啶A/4',6-二脒基-2-苯基吲哚)以及随后的4',6-二脒基-2-苯基吲哚/AMD染色(施韦泽,1981年)对三名“伯基特样”急性淋巴细胞白血病(FAB:L3)患者的骨髓和外周血进行了核型分析。在两名患者中我们发现了特异性易位t(8;22)。一名患者还表现出9号染色体的结构异常,使用DA/4',6-二脒基-2-苯基吲哚染色通过C带显像,并且在两名患者中我们发现了1号染色体的特异性异常。异常1号染色体的几种模式显示在拉长的长臂中有一个插入的DA/4',6-二脒基-2-苯基吲哚阳性C带。