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飞秒激光辅助散光性角膜切开术与植入散光人工晶状体矫正白内障患者散光的比较:一项采用序贯试验分析的系统评价和荟萃分析

Femtosecond laser-assisted astigmatic keratotomy versus toric IOL implantation for correcting astigmatism in cataract patients: a systematic review and meta-analysis with trial sequential analysis.

作者信息

Yen Wei-Ting, Weng Tzu-Heng, Lin Ting-Yi, Tai Ming-Cheng, Chen Yi-Hao, Chang Yu-Min

机构信息

Department of Ophthalmology, Tri-Service General Hospital, Taipei City, Taiwan.

National Defense Medical Center, Taipei City, Taiwan.

出版信息

Br J Ophthalmol. 2025 Feb 24;109(3):324-332. doi: 10.1136/bjo-2024-325195.

Abstract

AIMS

To compare the refractive and visual outcomes of femtosecond laser-assisted astigmatic keratotomy (FSAK) and toric intraocular lens (IOL) implantation for correcting astigmatism in cataract patients.

METHODS

Studies were retrieved from the Ovid-Medline, EMBASE, Cochrane Central Register of Controlled Trials and Scopus which compared FSAK and toric IOL for astigmatism correction in cataract patients. Outcome measures included postoperative refractive cylinder, correction index, uncorrected distance visual acuity (UDVA), the proportion of patients achieving a residual refractive cylinder of 1.00 dioptre or less, target-induced astigmatism (TIA) and surgically induced astigmatism (SIA). The trial sequential analysis (TSA) was used to collect firm evidence supporting our conclusion.

RESULTS

9 studies encompassing 590 participants were analysed. The meta-analysis revealed that toric IOLs could result in less postoperative refractive cylinder and provide better UDVA compared with FSAK. The TSA disclosed strong evidence of lower postoperative refractive cylinder in the toric IOL group compared with that of the FSAK group. FSAK showed a smaller correction index and lower mean TIA and SIA compared with toric IOLs.

CONCLUSIONS

For cataract patients, both FSAK and toric IOLs are effective methods for correcting astigmatism. However, toric IOLs offer less postoperative astigmatism and result in better postoperative UDVA compared with FSAK. In vector analysis of astigmatism, toric IOLs can also produce higher TIA and SIA. Additionally, neither method is associated with severe untreatable complications. Therefore, the conclusion is that toric IOLs are the preferred choice for astigmatism correction in cataract patients and FSAK serves as a viable alternative when toric IOLs are contraindicated.

摘要

目的

比较飞秒激光辅助散光性角膜切开术(FSAK)和植入散光人工晶状体(IOL)矫正白内障患者散光的屈光和视觉效果。

方法

从Ovid-Medline、EMBASE、Cochrane对照试验中央注册库和Scopus中检索比较FSAK和散光IOL矫正白内障患者散光的研究。结果指标包括术后屈光柱镜、矫正指数、未矫正远视力(UDVA)、残余屈光柱镜为1.00屈光度或更低的患者比例、目标诱导散光(TIA)和手术诱导散光(SIA)。采用试验序贯分析(TSA)收集支持我们结论的确凿证据。

结果

分析了9项研究,共590名参与者。荟萃分析显示,与FSAK相比,散光IOL可减少术后屈光柱镜并提供更好的UDVA。TSA显示有强有力的证据表明,与FSAK组相比,散光IOL组术后屈光柱镜更低。与散光IOL相比,FSAK的矫正指数更小,平均TIA和SIA更低。

结论

对于白内障患者,FSAK和散光IOL都是矫正散光的有效方法。然而,与FSAK相比,散光IOL术后散光更少,术后UDVA更好。在散光的矢量分析中,散光IOL也可产生更高的TIA和SIA。此外,两种方法均未出现严重的不可治疗并发症。因此,结论是散光IOL是白内障患者散光矫正的首选,当散光IOL禁忌时,FSAK是可行的替代方法。

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