Division of Gastroenterology and Hepatology, University Hospital Lausanne - CHUV, Lausanne Switzerland; Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland; Department of Internal Medicine, GZO - Zurich Regional Health Center, Spitalstrassse 66, Wetzikon 8610, Switzerland.
Division of Digestive and Liver Diseases, Presbyterian Hospital, 622 West 168th Street, New York, NY 10032, USA.
Immunol Allergy Clin North Am. 2024 May;44(2):357-368. doi: 10.1016/j.iac.2024.01.007. Epub 2024 Feb 13.
Endoscopic evaluation with biopsies is a mainstay of the diagnosis of eosinophilic esophagitis (EoE) and non-EoE eosinophilic gastrointestinal diseases (EGIDs). Increasing knowledge has resulted in the development of 2 standardized scoring systems: the Endoscopic REFerence Score (EREFS) for EoE and the EG-REFS for eosinophilic gastritis, although the latter has not been validated. In EGIDs, diagnosis and follow-up focus on eosinophil infiltration in biopsies. In this article, we will discuss the most commonly used endoscopic scores in EoE and non-EoE EGIDs, their validity for the diagnosis and follow-up of disease activity, as well as endoscopic interventions and areas of uncertainty.
内镜评估结合活检是嗜酸性食管炎（EoE）和非 EoE 嗜酸性胃肠道疾病（EGIDs）诊断的主要方法。随着知识的不断增加，已经开发出两种标准化评分系统：用于 EoE 的内镜参考评分（EREFS）和用于嗜酸性胃炎的 EG-REFS，尽管后者尚未得到验证。在 EGIDs 中，诊断和随访的重点是活检中的嗜酸性粒细胞浸润。在本文中，我们将讨论 EoE 和非 EoE EGIDs 中最常用的内镜评分，它们在疾病活动的诊断和随访中的有效性，以及内镜干预和不确定领域。
