Yellow Rose Headache and Neuro-Ophthalmology.
Neurol Clin. 2024 May;42(2):433-471. doi: 10.1016/j.ncl.2024.02.001.
Pseudotumor cerebri syndrome is a syndrome of increased cerebrospinal fluid pressure without ventriculomegaly, mass lesion, or meningeal abnormality. It is either primary (idiopathic intracranial hypertension, IIH) or secondary. A secondary cause is unlikely when adhering to the diagnostic criteria. Permanent visual loss occurs if undetected or untreated, and the associated headaches may be debilitating. Fulminant disease may result in blindness despite aggressive treatment. This study addresses the diagnosis and management of IIH including new insights into the pathobiology of IIH, updates in therapeutics and causes of overdiagnosis.
假性脑瘤综合征是一种脑脊液压升高而脑室无扩大、占位性病变或脑膜异常的综合征。它要么是原发性的(特发性颅内高压,IIH),要么是继发性的。如果符合诊断标准,继发性原因不太可能。如果未被发现或未得到治疗,永久性视力丧失会发生,而相关的头痛可能使人虚弱。尽管进行了积极治疗,暴发性疾病仍可能导致失明。本研究探讨了 IIH 的诊断和治疗,包括 IIH 的病理生物学的新见解、治疗方法的更新以及过度诊断的原因。