Department of Ophthalmology, Faculty of Medicine, Prince of Songkla University, 15, Kanjanavanich Road, Kohong, Hat Yai, Songkhla, 90110, Thailand.
BMC Ophthalmol. 2024 Apr 4;24(1):150. doi: 10.1186/s12886-024-03301-3.
Limited studies have reported surgical outcomes that are defined by strict criteria following grade 2 or 3 socket reconstruction using an oral mucosal graft (OMG). We aimed to determine factors influencing surgical outcomes of anophthalmic socket reconstruction using OMG in patients with grade 2 or 3 socket contractures.
Thirty-seven patients who underwent socket reconstruction with autologous OMG between January 2007 and December 2017 were retrospectively analyzed. The successful outcome was defined as an eye prosthesis wearing without experiencing displacement and the absence of any re-operations or additional surgeries following socket reconstruction. Factors affecting surgical outcomes were identified using multivariate analysis.
A total of 15 male and 22 female patients (mean age: 40.2 ± 17.2 years) were included. The median duration of socket contracture was 21.5 years. Grade 2 and 3 socket contractures, based on Tawfik's classification, were reported in 20 and 17 patients, respectively. Twenty-eight and eight patients underwent socket reconstruction using OMG alone and OMG combined with a hard palate graft, respectively. The success rates of grades 2 and 3 socket contracture reconstruction were 80.0% and 52.9%, respectively. Multivariate analysis demonstrated that only grade 3 contractures were predictive of worse outcomes. At the final visit (mean follow-up: 6.3 years), 34 patients (91.9%) could wear their eye prostheses.
Socket reconstruction using autologous OMG can provide acceptable results in grade 2 and 3 contractures; however, satisfactory results were more significantly reported in grade 2 than in grade 3 contractures.
仅有少数研究报告了使用口腔黏膜移植物（OMG）进行 2 级或 3 级 socket 重建后，根据严格标准定义的手术结果。我们旨在确定影响 2 级或 3 级 socket 挛缩患者使用 OMG 进行 anophthalmic socket 重建的手术结果的因素。
回顾性分析了 2007 年 1 月至 2017 年 12 月期间接受自体 OMG socket 重建的 37 例患者。成功的结果定义为佩戴义眼而不移位，且 socket 重建后无需进行任何再手术或其他手术。使用多变量分析确定影响手术结果的因素。
共有 15 名男性和 22 名女性患者（平均年龄：40.2±17.2 岁）纳入研究。 socket 挛缩的中位时间为 21.5 年。根据 Tawfik 分类，20 例患者为 2 级，17 例患者为 3 级 socket 挛缩。28 例患者仅使用 OMG，8 例患者使用 OMG 联合硬腭移植物进行 socket 重建。2 级和 3 级 socket 挛缩重建的成功率分别为 80.0%和 52.9%。多变量分析表明，只有 3 级挛缩是导致较差结果的预测因素。在最后一次就诊（平均随访：6.3 年）时，34 例患者（91.9%）能够佩戴义眼。
自体 OMG 进行 socket 重建可在 2 级和 3 级挛缩中提供可接受的结果；然而，在 2 级挛缩中报告的结果更显著，优于 3 级挛缩。
