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冷冻保存的超厚人羊膜在无眼窝畸形中的应用

Novel Use of Cryopreserved Ultra-thick Human Amniotic Membrane for Management of Anophthalmic Socket Contracture.

机构信息

Department of Ophthalmology and Visual Sciences, W. K Kellogg Eye Center, Ann Arbor, Michigan U.S.A.

出版信息

Ophthalmic Plast Reconstr Surg. 2019 Mar/Apr;35(2):193-196. doi: 10.1097/IOP.0000000000001264.

DOI:10.1097/IOP.0000000000001264
PMID:30407993
Abstract

PURPOSE

To describe the use of cryopreserved ultra-thick human amniotic membrane for management of anophthalmic socket contracture.

METHODS

A chart review was performed to identify patients undergoing fornix reconstruction with cryopreserved ultra-thick human amniotic membrane for management of anophthalmic socket contracture. Patient demographics, disease etiology, and data regarding postoperative prosthesis fit and complications were collected.

RESULTS

The technique is described in 3 female patients with anophthalmic socket contracture who underwent fornix reconstruction using cryopreserved ultra-thick human amniotic membrane. All patients had excellent prosthesis fit at final follow up (range, 10-14 months). There were no clinically significant complications and no reoperations were performed. One pyogenic granuloma developed and was excised without affecting ocular prosthesis fit.

CONCLUSIONS

Cryopreserved ultra-thick human amniotic membrane is easy to use, well tolerated, and produces good outcomes for management of anophthalmic socket contracture.

摘要

目的

描述使用冷冻保存的超厚人羊膜治疗无眼窝性眼眶收缩。

方法

进行病例回顾,以确定接受冷冻保存的超厚人羊膜穹窿重建以治疗无眼窝性眼眶收缩的患者。收集患者的人口统计学资料、疾病病因以及与术后义眼佩戴和并发症相关的数据。

结果

本技术在 3 例无眼窝性眼眶收缩的女性患者中进行了描述,她们均采用冷冻保存的超厚人羊膜进行穹窿重建。所有患者在最终随访时(10-14 个月)均具有良好的义眼佩戴效果。无明显临床并发症,也无需再次手术。有 1 例患者发生化脓性肉芽肿,切除后并未影响眼假体的佩戴效果。

结论

冷冻保存的超厚人羊膜易于使用,耐受性良好,对于治疗无眼窝性眼眶收缩效果良好。

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