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共聚焦激光内镜显微镜诊断低分化胃腺癌:一例报告

Diagnosis of poorly differentiated adenocarcinoma of the stomach by confocal laser endomicroscopy: A case report.

作者信息

Lou Jia-Xin, Wu Yong, Huhe Muren, Zhang Jing-Jie, Jia Dong-Wu, Jiang Zhen-Yu

机构信息

Department of Gastroenterology, The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014030, Inner Mongolia Autonomous Region, China.

Medical Innovation Center, The Fourth Military Medical University, Xi'an 710000, Shaanxi Province, China.

出版信息

World J Clin Cases. 2024 Mar 16;12(8):1481-1486. doi: 10.12998/wjcc.v12.i8.1481.

Abstract

BACKGROUND

In recent years, confocal laser endomicroscopy (CLE) has become a new endoscopic imaging technology at the microscopic level, which is extensively performed for real-time histological examination. CLE can be performed to distinguish benign from malignant lesions. In this study, we diagnosed using CLE an asymptomatic patient with poorly differentiated gastric adenocarcinoma.

CASE SUMMARY

A 63-year-old woman was diagnosed with gastric mucosal lesions, which may be gastric cancer, in the small curvature of the stomach by gastroscopy. She consented to undergo CLE for morphological observation of the gastric mucosa. Through the combination of CLE diagnosis and postoperative pathology, the intraoperative CLE diagnosis was considered to be reliable. According to our experience, CLE can be performed as the first choice for the diagnosis of gastric cancer.

CONCLUSION

CLE has several advantages over pathological diagnosis. We believe that CLE has great potential in the diagnosis of benign and malignant gastric lesions.

摘要

背景

近年来,共聚焦激光显微内镜检查(CLE)已成为一种新型的微观层面内镜成像技术,广泛用于实时组织学检查。CLE可用于区分良性和恶性病变。在本研究中,我们使用CLE诊断了一名无症状的低分化胃腺癌患者。

病例摘要

一名63岁女性经胃镜检查诊断为胃小弯处胃黏膜病变,可能为胃癌。她同意接受CLE以对胃黏膜进行形态学观察。通过CLE诊断与术后病理相结合,术中CLE诊断被认为是可靠的。根据我们的经验,CLE可作为胃癌诊断的首选方法。

结论

CLE相对于病理诊断具有多个优势。我们认为CLE在胃良恶性病变的诊断中具有巨大潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bfa/10989440/fcdebcf9d457/WJCC-12-1481-g001.jpg

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