Ayala-Garcia Amaia, Soldevila-Domenech Natalia, Yi So-Yun, de la Torre Rafael, Steffen Lyn M
Integrative Pharmacology and Systems Neurosciences Research Group, Neurosciences Research Program, Hospital del Mar Research Institute (HMRI), Barcelona, Spain.
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, United States.
Front Nutr. 2024 Mar 21;11:1379531. doi: 10.3389/fnut.2024.1379531. eCollection 2024.
The impact of dietary intake on cognitive outcomes and dementia prevention is a topic of increasing interest. Meta-analyses of observational studies, mostly conducted within US and European populations, have reported benefits of healthy diet patterns on cognitive performance, but results from individual studies have been inconsistent. These inconsistencies are likely due to the diverse methodology used in studies, including different diet and cognitive function assessment instruments, follow-up periods, and analytical methods, which make drawing conclusions relevant to dietary guidance challenging. The objective of this project is to describe a protocol to conduct a retrospective harmonization study on dietary intake and cognitive health using data from European and US studies. The recommendations resulting from the project can be used to support evidence-based synthesis for future iterations of the Dietary Guidelines for Americans or other population-based dietary guidance. Additionally, this study will serve as a harmonization guide for future research on the relationship between diet patterns and cognition. The approach outlined ultimately aims to optimize resources and expedite research efforts for dementia prevention.
饮食摄入对认知结果和痴呆预防的影响是一个越来越受关注的话题。大多在美国和欧洲人群中开展的观察性研究的荟萃分析报告了健康饮食模式对认知表现的益处，但个别研究的结果并不一致。这些不一致可能是由于研究中使用的方法多样，包括不同的饮食和认知功能评估工具、随访期以及分析方法，这使得得出与饮食指导相关的结论具有挑战性。本项目的目标是描述一项使用来自欧洲和美国研究的数据对饮食摄入与认知健康进行回顾性协调研究的方案。该项目产生的建议可用于支持为《美国膳食指南》或其他基于人群的饮食指导的未来版本进行循证综合。此外，本研究将作为未来饮食模式与认知关系研究的协调指南。最终概述的方法旨在优化资源并加快痴呆预防的研究工作。
