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术前参数(品种特征、数字 X 光、尿液分析、尿液微生物培养)和新型算法可提高犬尿囊结石成分预测的准确性。

Preoperative parameters (signalment, digital radiography, urinalysis, urine microbiological culture) and novel algorithm improve prediction of canine urocystolith composition.

机构信息

1Schwarzman Animal Medical Center, New York, NY.

2Division of Biostatistics, Department of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, NY.

出版信息

J Am Vet Med Assoc. 2024 Apr 5;262(8):1039-1046. doi: 10.2460/javma.23.12.0686. Print 2024 Aug 1.

DOI:10.2460/javma.23.12.0686
PMID:38579782
Abstract

OBJECTIVE

To determine the accuracy of 4 preoperative parameters (signalment, urinalysis, urine microbiological culture, and digital radiography) in predicting urocystolith composition, compare accuracy between evaluators of varying clinical experience and a mobile application, and propose a novel algorithm to improve accuracy.

ANIMALS

175 client-owned dogs with quantitative analyses of urocystoliths between January 1, 2012, and July 31, 2020.

METHODS

Prospective experimental study. Canine urocystolith cases were randomly presented to 6 blinded "stone evaluators" (rotating interns, radiologists, internists) in 3 rounds, each separated by 2 weeks: case data alone, case data with a urolith teaching lecture, and case data with a novel algorithm. Case data were also entered into the Minnesota Urolith Center mobile application. Prediction accuracy was determined by comparison to quantitative laboratory stone analysis results.

RESULTS

Prediction accuracy of evaluators varied with experience when shown case data alone (accuracy, 57% to 82%) but improved with a teaching lecture (accuracy, 76% to 89%) and further improved with a novel algorithm (accuracy, 93% to 96%). Mixed stone compositions were the most incorrectly predicted type. Mobile application accuracy was 74%.

CLINICAL RELEVANCE

Use of the 4 preoperative parameters resulted in variable accuracy of urocystolith composition predictions among evaluators. The proposed novel algorithm improves accuracy for all clinicians, surpassing accuracy of the mobile application, and may help guide patient management.

摘要

目的

确定 4 项术前参数(一般情况、尿液分析、尿液微生物培养和数字 X 线摄影)预测尿囊结石成分的准确性,比较不同临床经验评估者和移动应用程序之间的准确性,并提出一种新算法以提高准确性。

动物

2012 年 1 月 1 日至 2020 年 7 月 31 日期间,175 只接受过定量尿液分析的患犬。

方法

前瞻性实验研究。将犬尿囊结石病例随机呈现给 6 名盲法“结石评估者”(轮转住院医师、放射科医师、内科医师),共 3 轮,每轮间隔 2 周:仅病例数据、病例数据加尿石教学讲座和病例数据加新型算法。病例数据也输入明尼苏达州尿石中心移动应用程序。通过与定量实验室结石分析结果比较来确定预测准确性。

结果

当仅呈现病例数据时,评估者的预测准确性因经验而异(准确性为 57%至 82%),但通过教学讲座(准确性为 76%至 89%)和新型算法(准确性为 93%至 96%)可提高准确性。混合结石成分是最容易被错误预测的类型。移动应用程序的准确性为 74%。

临床意义

使用 4 项术前参数可导致评估者对尿囊结石成分预测的准确性不同。提出的新型算法可提高所有临床医生的准确性,超过移动应用程序的准确性,并可能有助于指导患者管理。

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