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脊髓损伤和神经源性膀胱患者的尿路感染诊断和管理注意事项。

Urinary Tract Infection Diagnostic and Management Considerations in People with Spinal Cord Injury and Neurogenic Bladder.

机构信息

Department of Medicine, Section of Infectious Diseases, VA Eastern Colorado Healthcare System, Aurora, CO, USA; Department of Medicine, Division of Infectious Diseases, University of Colorado Anschutz Medical Center, Aurora, CO, USA.

Department of Medicine, Division of Infectious Diseases, University of Colorado Anschutz Medical Center, CU Research Complex II, 12700 East 19th Avenue. Mail Stop B168, Aurora, CO 80045, USA.

出版信息

Infect Dis Clin North Am. 2024 Jun;38(2):381-393. doi: 10.1016/j.idc.2024.03.012. Epub 2024 Apr 4.

Abstract

Urinary tract infections (UTIs) are common complications in people with neurogenic bladder. Prevention, diagnosis, and treatment are challenging for several reasons, including a high prevalence of asymptomatic bacteriuria and catheter use, frequent ambiguous nonlocalizing signs and symptoms, increased risk for complications and difficult-to-treat pathogens, and a lack of effective preventative methods. Current research aims to improve elicitation and evaluation of signs and symptoms, implement algorithms to avoid urine cultures in asymptomatic patients and use appropriate antibiotics for UTI, and identify novel effective prevention methods.

摘要

尿路(UTI)感染是神经原性膀胱患者的常见并发症。由于多种原因,包括无症状菌尿和导尿管使用的高流行率、频繁出现的模糊非定位症状和体征、并发症和难以治疗的病原体风险增加,以及缺乏有效的预防方法,预防、诊断和治疗都具有挑战性。目前的研究旨在改善症状的引出和评估,实施算法以避免无症状患者进行尿液培养并使用适当的抗生素治疗 UTI,并确定新的有效预防方法。

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