Centre for Big Data Research in Health, University of New South Wales, Sydney, NSW, Australia.
Department of Cardiothoracic Surgery, Prince of Wales Hospital, Sydney, NSW, Australia.
Heart Lung Circ. 2024 Jul;33(7):1027-1035. doi: 10.1016/j.hlc.2024.02.012. Epub 2024 Apr 4.
In Australia, transcatheter aortic valve implantation (TAVI) is only performed in a limited number of specialised metropolitan centres, many of which are private hospitals, making it likely that TAVI patients who require readmission will present to another (non-index) hospital. It is important to understand the impact of non-index readmission on patient outcomes and healthcare resource utilisation.
We analysed linked hospital and death records for residents of New South Wales, Australia, aged ≥18 years, who had an emergency readmission within 90 days following a TAVI procedure in 2013-2022. Mixed-effect, multi-level logistic regression models were used to evaluate predictors of non-index readmission, and associations between non-index readmission and readmission length of stay, 90-day mortality, and 1-year mortality.
Of 4,198 patients (mean age, 82.7 years; 40.6% female) discharged alive following TAVI, 933 (22.2%) were readmitted within 90 days of discharge. Over three-quarters (76.0%) of those readmitted returned to a non-index hospital, with no significant difference in readmission principal diagnosis between index hospital and non-index hospital readmissions. Among readmitted patients, independent predictors of non-index readmission included: residence in regional or remote areas, lower socio-economic status, having a pre-procedure transfer, and a private index hospital. Readmission length of stay (median, 4 days), 90-day mortality (adjusted odds ratio [OR] 1.04, 95% confidence interval [CI] 0.56-1.96) and 1-year mortality (adjusted OR 1.01, 95% CI 0.64-1.58) were similar between index and non-index readmissions.
Non-index readmission following TAVI was highly prevalent but not associated with increased mortality or healthcare utilisation. Our results are reassuring for TAVI patients in regional and remote areas with limited access to return to index TAVI hospitals.
在澳大利亚,经导管主动脉瓣植入术(TAVI)仅在少数专门的大都市中心进行,其中许多是私立医院,这使得需要再次入院的 TAVI 患者很可能会前往另一家(非索引)医院。了解非索引再入院对患者结局和医疗资源利用的影响很重要。
我们分析了 2013 年至 2022 年期间在澳大利亚新南威尔士州接受 TAVI 手术后 90 天内紧急再入院的年龄≥18 岁的居民的医院和死亡记录。使用混合效应、多水平逻辑回归模型来评估非索引再入院的预测因素,以及非索引再入院与再入院住院时间、90 天死亡率和 1 年死亡率之间的关联。
在 4198 名(平均年龄 82.7 岁;40.6%为女性)TAVI 术后存活出院的患者中,933 名(22.2%)在出院后 90 天内再次入院。其中超过四分之三(76.0%)的再入院患者返回非索引医院,索引医院和非索引医院的再入院主要诊断无显著差异。在再入院患者中,非索引再入院的独立预测因素包括:居住在地区或偏远地区、社会经济地位较低、术前转院以及索引医院为私立医院。再入院住院时间(中位数为 4 天)、90 天死亡率(调整后比值比 [OR] 1.04,95%置信区间 [CI] 0.56-1.96)和 1 年死亡率(调整后 OR 1.01,95% CI 0.64-1.58)在索引和非索引再入院之间相似。
TAVI 后非索引再入院的发生率很高,但与死亡率或医疗资源利用的增加无关。对于区域和偏远地区 TAVI 患者,由于返回索引 TAVI 医院的机会有限,我们的结果令人感到安心。