Shawon Md Shajedur Rahman, Lujic Sanja, Joshi Yashutosh, Jorm Louisa
Centre for Big Data Research in Health, University of New South Wales, Sydney, Australia.
Department of Cardiothoracic and Transplant Surgery, St Vincent's Hospital, Sydney, Australia.
Lancet Reg Health West Pac. 2024 Sep 4;51:101189. doi: 10.1016/j.lanwpc.2024.101189. eCollection 2024 Oct.
It is unclear how pre-surgery transfer relates to readmission destination among patients undergoing cardiac surgery and whether readmission to a hospital other than the operating hospital is associated with increased mortality.
We analysed linked hospital and death records for residents of New South Wales, Australia, aged ≥18 years who had an emergency readmission within 30 days following coronary artery bypass graft (CABG) or surgical aortic valve replacement (SAVR) in 2003-2022. Mixed-effect multi-level modelling was used to evaluate associations of readmission destination with 30-day mortality, overall and stratified by pre-surgery transfer.
Of 102,540 patients undergoing cardiac surgery (isolated CABG = 63,000, SAVR = 27,482, combined = 12,058), 28.7% (n = 29,398) had pre-surgery transfer, while the 30-day readmission rate was 14.7% (n = 14,708). During readmission, 35.7% (3499/9795) of those without pre-surgery transfer and 12.0% (590/4913) of those with pre-surgery transfer returned to the operating hospital. Among readmitted patients, 30-day mortality did not differ significantly for those who were readmitted to a non-index hospital, both overall (adjusted odds ratio [aOR] = 1.03 95% CI 0.75-1.41), and in analyses stratified by pre-surgery transfer (no transfer: aOR = 1.07, 95% CI 0.75-1.52; transfer: aOR = 0.88, 95% CI 0.45-1.72). Among patients who had pre-surgery transfer, 30-day mortality was similar among patients who were readmitted to the index operating hospital (reference), the initial admitting hospital (aOR = 1.00, 95% CI 0.50-2.00) or a third, different, hospital (aOR = 0.70, 95% CI 0.33-1.48).
Although many Australian patients who are readmitted following cardiac surgery are readmitted to hospitals different to the operating or initial admitting hospital, such readmissions are not associated with increased mortality.
This study was funded by a National Health and Medical Research Foundation of Australia (NHMRC) Project Grant (#1162833).
目前尚不清楚心脏手术患者术前转院与再入院目的地之间的关系,以及再次入住非手术医院是否与死亡率增加相关。
我们分析了澳大利亚新南威尔士州年龄≥18岁居民在2003年至2022年接受冠状动脉搭桥术(CABG)或外科主动脉瓣置换术(SAVR)后30天内紧急再入院的医院和死亡记录。采用混合效应多级模型评估再入院目的地与30天死亡率之间的关联,并按术前转院情况进行总体和分层分析。
在102540例接受心脏手术的患者中(单纯CABG = 63000例,SAVR = 27482例,联合手术 = 12058例),28.7%(n = 29398)有术前转院,而30天再入院率为14.7%(n = 14708)。再入院期间,术前未转院的患者中有35.7%(3499/9795)、术前转院的患者中有12.0%(590/4913)返回手术医院。在再入院患者中,再次入住非索引医院的患者30天死亡率在总体上(调整优势比[aOR]=1.03,95%可信区间0.75-1.41)以及按术前转院分层分析时均无显著差异(未转院:aOR = 1.07,95%可信区间0.75-1.52;转院:aOR = 0.88,95%可信区间0.45-1.72)。在有术前转院的患者中,再次入住索引手术医院(参照)、最初收治医院(aOR = 1.00,95%可信区间0.50-2.00)或第三家不同医院(aOR = 0.70,95%可信区间0.33-1.48)的患者30天死亡率相似。
尽管许多澳大利亚心脏手术后再入院的患者被再次收治到与手术或最初收治医院不同的医院,但这种再入院与死亡率增加无关。
本研究由澳大利亚国家卫生与医学研究委员会(NHMRC)项目基金(#1162833)资助。