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Masquelet技术联合游离皮瓣技术与Ilizarov骨搬运技术治疗严重胫腓骨复合组织缺损的比较

Masquelet combined with free-flap technique versus the Ilizarov bone transport technique for severe composite tibial and soft-tissue defects.

作者信息

Zhang Qingqing, Kang Yongqiang, Wu Yongwei, Ma Yunhong, Jia Xueyuan, Zhang Mingyu, Lin Fang, Rui Yongjun

机构信息

Department of Traumatic Orthopedics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, China.

Department of Traumatic Orthopedics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, China; Medical College, Soochow University, Suzhou, Jiangsu, China.

出版信息

Injury. 2024 Jun;55(6):111521. doi: 10.1016/j.injury.2024.111521. Epub 2024 Apr 4.

Abstract

BACKGROUND

The treatment of bone and soft-tissue defects after open fractures remains challenging. This study aimed to evaluate the clinical efficacy of the Masquelet technique combined with the free-flap technique (MFFT) versus the Ilizarov bone transport technique (IBTT) for the treatment of severe composite tibial and soft-tissue defects.

METHODS

We retrospectively analysed the data of 65 patients with tibial and soft-tissue defects and Gustilo type IIIB/C open fractures treated at our hospital between April 2015 and December 2021. The patients were divided into two groups based on the treatment method: group A (n = 35) was treated with the MFFT and internal fixation, and group B (n = 30) was treated with the IBTT.

RESULTS

The mean follow-up period was 28 months (range 13-133 months). Complete union of both soft-tissue and bone defects was achieved in all cases. The mean bone-union times were 6 months (range 3-12 months) in group A and 11 months (range 6-23 month) in group B, with a significant difference between the two groups (Z = -4.11, P = 0.001). The mean hospital stay was 28 days (range 14-67 d) in group A which was significantly longer than the mean stay of 18 days (range 10-43 d) in group B (Z = -2.608, P = 0.009). There were no significant differences in the infection rate between group A (17.1 %) and group B (26.7%) (χ = 0.867, P = 0.352). The Total Physical Health Scores were 81.51 ± 6.86 (range 67-90) in group A and 75.83±16.14 (range 44-98) in group B, with no significant difference between the two groups (t = 1.894, P = 0.063). The Total Mental Health Scores were significantly higher in group A (90.49 ± 6.37; range 78-98) than in group B (84.70 ± 13.72; range 60-98) (t = 2.232, P = 0.029).

CONCLUSION

Compared with IBTT, MFFT is a better choice of treatment for open tibial and soft-tissue defects with Gustilo IIIB/C fractures. IBTT is the preferred option when the tibial bone defect is large or if the surgeon's expertise in microsurgery is limited.

摘要

背景

开放性骨折后骨与软组织缺损的治疗仍然具有挑战性。本研究旨在评估Masquelet技术联合游离皮瓣技术(MFFT)与Ilizarov骨搬运技术(IBTT)治疗严重胫腓骨复合软组织缺损的临床疗效。

方法

我们回顾性分析了2015年4月至2021年12月在我院接受治疗的65例胫腓骨及软组织缺损合并Gustilo IIIB/C型开放性骨折患者的数据。根据治疗方法将患者分为两组:A组(n = 35)采用MFFT及内固定治疗,B组(n = 30)采用IBTT治疗。

结果

平均随访时间为28个月(范围为13 - 13三个月)。所有病例的软组织和骨缺损均完全愈合。A组平均骨愈合时间为6个月(范围3 - 12个月),B组为11个月(范围6 - 23个月),两组间差异有统计学意义(Z = -4.11,P = 0.001)。A组平均住院时间为28天(范围14 - 67天),显著长于B组的平均住院时间18天(范围10 - 43天)(Z = -2.608,P = 0.009)。A组感染率为17.1%,B组为26.7%,两组感染率差异无统计学意义(χ = 0.867,P = 0.352)。A组总体身体健康评分为81.51 ± 6.86(范围67 - 90),B组为75.83±16.14(范围44 - 98),两组间差异无统计学意义(t = 1.894,P = 0.063)。A组总体心理健康评分显著高于B组(90.49 ± 6.37;范围78 - 98)(84.70 ± 13.72;范围60 - 98)(t = 2.232,P = 0.029)。

结论

与IBTT相比,MFFT是治疗Gustilo IIIB/C型开放性胫腓骨及软组织缺损的更好选择。当胫骨骨缺损较大或外科医生显微外科专业技能有限时,IBTT是首选方案。

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