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老年患者射频消融治疗甲状旁腺功能亢进合并急性胰腺炎:一例报告

Hyperparathyroidism with acute pancreatitis in elderly patient treated by radiofrequency ablation: A case report.

作者信息

Anh Tran Thi Hoang, My Le Thi, Tu Ngo Thi Thanh, Hiep Pham Vu, My Thieu Thi Tra

机构信息

Radiology department, Vinmec Times City International hospital, Ha Noi, Viet Nam.

出版信息

Radiol Case Rep. 2024 Mar 28;19(6):2438-2442. doi: 10.1016/j.radcr.2024.02.082. eCollection 2024 Jun.

DOI:10.1016/j.radcr.2024.02.082
PMID:38585396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10997866/
Abstract

Acute pancreatitis as an initial manifestation of primary hyperparathyroidism (PHPT) has been rarely reported. We report a case of acute pancreatitis from a hyperfunctioning parathyroid tumor in an 87-year-old woman with drowsy state. Laboratory tests showed high lipase, calcium, and intact parathyroid hormone level, and abdominal computed tomography scan revealed acute pancreatitis. Neck ultrasound and scintigraphy gave rise to the diagnosis of primary hyperparathyroidism due to a left parathyroid tumor. The patient underwent radiofrequency ablation of the parathyroid tumor. After the procedure, symptoms subsided and patient was discharged from the hospital 2 weeks later. Six months of treatment, the PTH and calcium serum significantly reduced, her clinical presentation was stable, and there were no signs or symptoms of recurrence pancreatitis.

摘要

急性胰腺炎作为原发性甲状旁腺功能亢进症(PHPT)的初始表现鲜有报道。我们报告一例87岁嗜睡女性因甲状旁腺功能亢进肿瘤引发急性胰腺炎的病例。实验室检查显示脂肪酶、钙和甲状旁腺激素水平升高,腹部计算机断层扫描显示为急性胰腺炎。颈部超声和闪烁扫描诊断为左侧甲状旁腺肿瘤导致的原发性甲状旁腺功能亢进症。患者接受了甲状旁腺肿瘤的射频消融术。术后症状缓解,患者于2周后出院。经过6个月的治疗,血清甲状旁腺激素(PTH)和钙显著降低,临床表现稳定,无胰腺炎复发的迹象或症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/f01307a7d64d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/d741a978798e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/3508ad890434/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/f01307a7d64d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/d741a978798e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/3508ad890434/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc2c/10997866/f01307a7d64d/gr3.jpg

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本文引用的文献

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World J Gastrointest Pharmacol Ther. 2022 Jul 5;13(4):47-56. doi: 10.4292/wjgpt.v13.i4.47.
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Efficacy and safety of radiofrequency ablation versus parathyroidectomy for secondary hyperparathyroidism in dialysis patients: a single-center retrospective study.射频消融与甲状旁腺切除术治疗透析患者继发性甲状旁腺功能亢进症的疗效和安全性:一项单中心回顾性研究。
Sci Rep. 2022 Jun 18;12(1):10289. doi: 10.1038/s41598-022-14623-x.
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Ultrasound-guided microwave and radiofrequency ablation for primary hyperparathyroidism: a prospective, multicenter study.
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