碘介导的吲哚啉与唑类和重氮盐的氧化三官能团化反应。
Iodine-mediated oxidative triple functionalization of indolines with azoles and diazonium salts.
作者信息
Liu Yifeng, Gu Xiaoting, Zhang Xiaoxiang, Xu Meilan, Zhang Zhuan, Liang Taoyuan
机构信息
Guangxi Key Laboratory of Electrochemical Energy Materials, Guangxi Colleges and Universities Key Laboratory of Applied Chemistry Technology and Resource Development, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi 530004, People's Republic of China.
出版信息
Chem Commun (Camb). 2024 Apr 23;60(34):4613-4616. doi: 10.1039/d4cc00856a.
We report an innovative synthetic strategy for the generation of polysubstituted indoles from indolines, aryldiazonium salts, and azoles. The methodology encompasses an electrophilic substitution reaction affording C5-indoline intermediates which undergo an iodine-mediated oxidative transformation coupled with C-H functionalization to yield the indole derivatives.
我们报道了一种由二氢吲哚、芳基重氮盐和唑类化合物生成多取代吲哚的创新合成策略。该方法包括亲电取代反应，生成C5-二氢吲哚中间体，该中间体经过碘介导的氧化转化与C-H官能化反应，生成吲哚衍生物。
Zotero 插件