Elite Laser Clinic, Madrid, Spain.
J Cosmet Dermatol. 2024 Apr;23 Suppl 1:13-18. doi: 10.1111/jocd.16283.
Scarring is one of the most prevalent long-term complications of acne vulgaris and has cosmetic, psychological, and social burdens. Contemporary management programs integrate multiple modalities to best address the multiple factors underlying their development and persistence. This work assessed the impact of sequential multimodal laser therapy on acne scar geometrics and texture.
Adult patients (n = 16) with Fitzpatrick skin type II-IV and presenting with facial acne scars, underwent three combination ablative (CO), and nonablative (1570 nm) laser treatment sessions at two-month intervals. Treatment was delivered using a ProScan Hybrid applicator, with each regimen including illumination with both ablative and a nonablative lasers applied in a grid mode sequence. Scar microtopography was assessed at baseline and 6 months after the last treatment session.
At baseline, all patients had both box and rolling scars, while only three had icepick scars. Six months following treatment, mean scar volume improved from 5.7 ± 5.2 mm at baseline to 3.1 ± 3.0 mm and mean affected area improved from 165.6 ± 134.0 mm 94.0 ± 80.1 mm, translating to 47.0 ± 7.9% and 43.2 ± 8.6% reductions from baseline, respectively. Patients were highly satisfied with treatment outcomes, and no serious adverse reactions were documented during the course of treatment or follow-up.
Multimodal CO and 1570-nm laser treatment improved the surface profilometry of patients with atrophic facial acne scars. Customization of both treatment intervals and laser settings to cosmetic regions, scar profiles and skin phototypes may further enhance treatment outcomes and expand its applicability to additional skin deformities.
瘢痕是寻常型痤疮最常见的长期并发症之一,给患者带来了美容、心理和社会负担。目前的治疗方案整合了多种手段,以最佳方式解决其发病和持续存在的多种因素。本研究评估了序贯多模态激光治疗对面部痤疮瘢痕形态和质地的影响。
16 名成人患者(Fitzpatrick 皮肤类型 II-IV 型),面部有痤疮瘢痕,每 2 个月接受 3 次组合消融(CO)和非消融(1570nm)激光治疗。采用 ProScan Hybrid 治疗头进行治疗,每个方案包括以网格模式顺序应用消融和非消融激光照射。在基线和最后一次治疗后 6 个月评估瘢痕微地形。
基线时,所有患者均有箱型和滚动型瘢痕,仅 3 例有冰锥型瘢痕。治疗 6 个月后,瘢痕体积从基线时的 5.7±5.2mm 改善至 3.1±3.0mm,受累面积从 165.6±134.0mm 改善至 94.0±80.1mm,分别改善了 47.0±7.9%和 43.2±8.6%。患者对治疗效果非常满意,治疗过程中和随访期间均未出现严重不良反应。
CO 和 1570nm 激光序贯治疗可改善面部萎缩性痤疮瘢痕患者的表面轮廓。根据美容区域、瘢痕形态和皮肤光型定制治疗间隔和激光参数,可能进一步提高治疗效果,并将其应用于更多的皮肤畸形。