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剥脱性分数激光联合非剥脱性激光治疗亚洲患者痤疮瘢痕的临床试验。

Clinical trial of dual treatment with an ablative fractional laser and a nonablative laser for the treatment of acne scars in Asian patients.

作者信息

Kim Sangeun, Cho Kyeong-Hun

机构信息

Department of Dermatology, Yonsei-Zium Skin Laser Clinic, Seoul, Korea.

出版信息

Dermatol Surg. 2009 Jul;35(7):1089-98. doi: 10.1111/j.1524-4725.2009.01193.x. Epub 2009 Apr 28.

Abstract

BACKGROUND

Many methods have been proposed for the treatment of acne scars, with variable cosmetic results. Nonablative skin resurfacing is one method that has been proposed. Because of a need for more noticeable clinical improvements, the ablative fractional laser was recently introduced.

OBJECTIVE

To reduce complications and improve the results of ablative fractional laser resurfacing by combining this treatment of acne scars with nonablative lasers.

METHODS

A series of 20 patients (skin phototypes IV-V) with atrophic facial acne scars were randomly divided into two groups that received three successive monthly treatments with an ablative fractional laser using high (group A) and low (group B) energy on one facial half and an ablative fractional laser with low energy plus a nonablative resurfacing laser on the other facial half. Patients were evaluated using digital photography at each treatment visit and at 3 months postoperatively. Clinical assessment scores were determined at each treatment session and follow-up visit.

RESULTS

Although the use of the ablative fractional laser with high energy resulted in an improvement in patients' acne scars, the combination of ablative fractional laser resurfacing and nonablative laser resurfacing yielded the best results, as assessed in photographs as well as by the overall appearance of the acne scars. With the combination method, fewer complications were observed.

摘要

背景

已经提出了许多治疗痤疮瘢痕的方法,其美容效果各不相同。非剥脱性皮肤重建是已被提出的一种方法。由于需要更显著的临床改善,最近引入了剥脱性分次激光。

目的

通过将这种痤疮瘢痕治疗方法与非剥脱性激光相结合,减少并发症并改善剥脱性分次激光重建的效果。

方法

将一系列20例(皮肤光型为IV - V型)面部萎缩性痤疮瘢痕患者随机分为两组,每组在一侧面部接受连续三个月每月一次的剥脱性分次激光治疗,A组采用高能量,B组采用低能量,另一侧面部接受低能量剥脱性分次激光加非剥脱性重建激光治疗。在每次治疗就诊时和术后3个月使用数码摄影对患者进行评估。在每次治疗 session 和随访就诊时确定临床评估分数。

结果

尽管使用高能量剥脱性分次激光可改善患者的痤疮瘢痕,但根据照片以及痤疮瘢痕的整体外观评估,剥脱性分次激光重建与非剥脱性激光重建相结合产生了最佳效果。采用联合方法时,观察到的并发症较少。

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