Park Hahnnah, Hong Sandy, Chrzan Brian, Al-Talib Tanya, Abubakr Neamat Hassan
School of Dental Medicine, University of Nevada, Las Vegas, NV, USA.
J Orthod. 2025 Mar;52(1):72-81. doi: 10.1177/14653125241244806. Epub 2024 Apr 8.
To evaluate the aesthetic outcome by varying the duration allowed for infiltrant penetration when treating white spot lesions with resin infiltration.
An in vitro, experimental randomised study.
Artificially created white spot lesions (WSLs) were induced on 100 extracted anterior teeth (T1). Teeth were divided into enamel and dentine groups depending on the extent of the lesion and then randomly assigned into different treatment protocol groups: penetration times of 3, 6 and 9 min. Resin infiltration treatment was applied according to the treatment protocol assigned (T2). Samples were thermocycled for 10,000 cycles (1 clinical year) (T3). The samples from the 3-min enamel and dentine groups were then randomly assigned into either a repeat treatment or no additional treatment group (T4). Samples were then thermocycled for an additional 10,000 cycles (T5). Spectrophotometric analysis was measured colour change (ΔE) for all groups.
Mean ΔE values equal to or greater than the critical value (3.7) indicate a detectable clinical difference in colour of the treated WSL when compared to before WSL formation. Mean ΔE values, for the enamel groups, were slightly above or significantly below the critical value, and for the dentine groups, were significantly above the critical value. Mean ΔE values within the enamel and dentine groups both demonstrated a downward trend with increasing time allowed for resin infiltrant penetration ( < 0.05). No significant mean ΔE difference ( = 0.53) was found between groups that received a single or repeat treatment. After the first thermocycling event, no significant difference in colour change was observed in all groups except for the deep dentine lesion treated for 3 min. There was a significant difference in colour change for all groups except the enamel group that received a single treatment following thermocycling after a single or repeat treatment.
Increasing the resin infiltrant penetration time to at least 9 min is advised as the most optimised treatment protocol. Resin infiltration treatment should be done only once to treat a particular white spot lesion as subsequent treatment for the same lesion results in marginal colour improvement. The colour improvement of WSLs resulting from the resin infiltration treatment can be expected to last for at least 1 year. Resin infiltration treatment of shallow lesions with a single and optimised infiltration technique can be expected to last an additional year.
通过改变树脂浸润治疗白斑病变时浸润剂渗透的持续时间来评估美学效果。
一项体外实验性随机研究。
在100颗拔除的前牙（T1）上人工诱导产生白斑病变（WSLs）。根据病变程度将牙齿分为釉质组和牙本质组，然后随机分为不同的治疗方案组：渗透时间分别为3分钟、6分钟和9分钟。根据分配的治疗方案进行树脂浸润治疗（T2）。样本进行10000次热循环（相当于1个临床年）（T3）。然后将3分钟釉质组和牙本质组的样本随机分为重复治疗组或不进行额外治疗组（T4）。样本再进行额外的10000次热循环（T5）。通过分光光度分析测量所有组的颜色变化（ΔE）。
平均ΔE值等于或大于临界值（3.7）表明与白斑病变形成前相比，治疗后的白斑病变颜色有可检测到的临床差异。对于釉质组，平均ΔE值略高于或显著低于临界值，而对于牙本质组，平均ΔE值显著高于临界值。釉质组和牙本质组内的平均ΔE值均随着树脂浸润剂渗透时间的增加呈下降趋势（P<0.05）。接受单次或重复治疗的组之间未发现显著的平均ΔE差异（P = 0.53）。在第一次热循环事件后，除了3分钟治疗的深层牙本质病变外，所有组在颜色变化方面均未观察到显著差异。在单次或重复治疗后的热循环后，除了接受单次治疗的釉质组外，所有组在颜色变化方面均存在显著差异。
建议将树脂浸润剂渗透时间增加至至少9分钟作为最优化的治疗方案。对于特定的白斑病变，树脂浸润治疗应仅进行一次，因为对同一病变的后续治疗在颜色改善方面效果甚微。树脂浸润治疗导致的白斑病变颜色改善预计至少可持续1年。采用单一且优化的浸润技术对浅病变进行树脂浸润治疗预计可再持续1年。
