Onkoderma-Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia, Bulgaria.
Department of Common, Abdominal and Vascular Surgery, Medical Institute of Ministry of Interior, Sofia, Bulgaria.
Wien Med Wochenschr. 2024 Nov;174(15-16):342-349. doi: 10.1007/s10354-024-01039-7. Epub 2024 Apr 8.
Giant condyloma acuminatum (GCA), alternatively referred to as a Buschke-Löwenstein tumor (BLT), is an uncommon, benign, but locally aggressive form of verrucous carcinoma. The condition usually affects the male population under the age of 50 years; however, there have been rare reports of pediatric cases. Various risk factors such as smoking, diabetes, promiscuous behavior, poor hygiene, immunosuppression, and others are linked to the development of this condition. We present the case of a 26-year-old male patient who came to the dermatology department with primary complaints of 10-year-old verrucous tumor formations located in the perigenital and perianal areas. Serological tests for AIDS, hepatitis B, hepatitis C, Chlamydia trachomatis, and syphilis were negative. The routine blood tests were slightly abnormal. Histological verification of condylomata acuminata of Buschke-Löwenstein was made. Given the sensitive areas, surgery was advised. With several fine undermining scalpel excisions, the lesions in the scrotal and perigenital areas were removed and the dartos muscle was preserved. Electrodissection and shave curettage were not performed. The postoperative period passed without complications and no recurrences in the perigenital area were reported. We believe that our case report represents the first documented surgical approach for scrotal Buschke-Löwenstein tumor using exclusively fine undermining scalpel surgery. A brief literature review of the condition is presented, focusing on the currently available treatment options and highlighting the potential effectiveness of the surgical approach.
巨大尖锐湿疣(GCA),也称为 Buschke-Löwenstein 肿瘤(BLT),是一种罕见的良性但局部侵袭性的疣状癌。这种情况通常影响 50 岁以下的男性人群;然而,也有罕见的儿科病例报告。各种风险因素,如吸烟、糖尿病、滥交、卫生条件差、免疫抑制等,与这种情况的发展有关。我们报告了一名 26 岁男性患者的病例,他因生殖器和肛门周围有 10 年的疣状肿瘤形成而到皮肤科就诊。艾滋病、乙型肝炎、丙型肝炎、沙眼衣原体和梅毒的血清学检测均为阴性。常规血液检查略有异常。组织学验证为 Buschke-Löwenstein 的尖锐湿疣。鉴于敏感部位,建议手术。通过多次精细的皮下手术刀切除,阴囊和生殖器周围的病变被切除,并保留了腹外斜肌腱膜。未进行电切和刮除术。术后无并发症,生殖器周围无复发。我们认为我们的病例报告代表了首例使用纯精细皮下手术刀手术治疗阴囊 Buschke-Löwenstein 肿瘤的手术方法。对该病进行了简要的文献复习,重点介绍了目前可用的治疗选择,并强调了手术方法的潜在有效性。