• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

精细刀法手术:保留鞘膜肌在患有阴囊和会阴巨大 Buschke-Löwenstein 肿瘤的患者中。

Fine scalpel surgery: preserving the dartos muscle in a patient with scrotal and perigenital giant Buschke-Löwenstein tumors.

机构信息

Onkoderma-Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia, Bulgaria.

Department of Common, Abdominal and Vascular Surgery, Medical Institute of Ministry of Interior, Sofia, Bulgaria.

出版信息

Wien Med Wochenschr. 2024 Nov;174(15-16):342-349. doi: 10.1007/s10354-024-01039-7. Epub 2024 Apr 8.

DOI:10.1007/s10354-024-01039-7
PMID:38587714
Abstract

Giant condyloma acuminatum (GCA), alternatively referred to as a Buschke-Löwenstein tumor (BLT), is an uncommon, benign, but locally aggressive form of verrucous carcinoma. The condition usually affects the male population under the age of 50 years; however, there have been rare reports of pediatric cases. Various risk factors such as smoking, diabetes, promiscuous behavior, poor hygiene, immunosuppression, and others are linked to the development of this condition. We present the case of a 26-year-old male patient who came to the dermatology department with primary complaints of 10-year-old verrucous tumor formations located in the perigenital and perianal areas. Serological tests for AIDS, hepatitis B, hepatitis C, Chlamydia trachomatis, and syphilis were negative. The routine blood tests were slightly abnormal. Histological verification of condylomata acuminata of Buschke-Löwenstein was made. Given the sensitive areas, surgery was advised. With several fine undermining scalpel excisions, the lesions in the scrotal and perigenital areas were removed and the dartos muscle was preserved. Electrodissection and shave curettage were not performed. The postoperative period passed without complications and no recurrences in the perigenital area were reported. We believe that our case report represents the first documented surgical approach for scrotal Buschke-Löwenstein tumor using exclusively fine undermining scalpel surgery. A brief literature review of the condition is presented, focusing on the currently available treatment options and highlighting the potential effectiveness of the surgical approach.

摘要

巨大尖锐湿疣(GCA),也称为 Buschke-Löwenstein 肿瘤(BLT),是一种罕见的良性但局部侵袭性的疣状癌。这种情况通常影响 50 岁以下的男性人群;然而,也有罕见的儿科病例报告。各种风险因素,如吸烟、糖尿病、滥交、卫生条件差、免疫抑制等,与这种情况的发展有关。我们报告了一名 26 岁男性患者的病例,他因生殖器和肛门周围有 10 年的疣状肿瘤形成而到皮肤科就诊。艾滋病、乙型肝炎、丙型肝炎、沙眼衣原体和梅毒的血清学检测均为阴性。常规血液检查略有异常。组织学验证为 Buschke-Löwenstein 的尖锐湿疣。鉴于敏感部位,建议手术。通过多次精细的皮下手术刀切除,阴囊和生殖器周围的病变被切除,并保留了腹外斜肌腱膜。未进行电切和刮除术。术后无并发症,生殖器周围无复发。我们认为我们的病例报告代表了首例使用纯精细皮下手术刀手术治疗阴囊 Buschke-Löwenstein 肿瘤的手术方法。对该病进行了简要的文献复习,重点介绍了目前可用的治疗选择,并强调了手术方法的潜在有效性。

相似文献

1
Fine scalpel surgery: preserving the dartos muscle in a patient with scrotal and perigenital giant Buschke-Löwenstein tumors.精细刀法手术:保留鞘膜肌在患有阴囊和会阴巨大 Buschke-Löwenstein 肿瘤的患者中。
Wien Med Wochenschr. 2024 Nov;174(15-16):342-349. doi: 10.1007/s10354-024-01039-7. Epub 2024 Apr 8.
2
Squamous Cell Carcinoma Arising from Perianal Buschke-Lowenstein Tumor (Giant Condyloma Acuminatum): Comprehensive Literature Review.肛门周围 Buschke-Lowenstein 肿瘤(巨大尖锐湿疣)继发鳞癌:全面文献复习。
J Gastrointest Cancer. 2022 Dec;53(4):1083-1092. doi: 10.1007/s12029-021-00713-y. Epub 2021 Oct 25.
3
[Pedunculated Giant Condyloma Acuminatum of the Scrotum].[阴囊带蒂巨大尖锐湿疣]
Hinyokika Kiyo. 2024 May;70(5):129-131. doi: 10.14989/ActaUrolJap_70_5_129.
4
Rapidly Invasive Buschke-Löwenstein Tumor Associated With Human Papillomavirus Types 6 and 52.与6型和52型人乳头瘤病毒相关的快速侵袭性Buschke-Löwenstein肿瘤
Sex Transm Dis. 2015 Oct;42(10):547-8. doi: 10.1097/OLQ.0000000000000346.
5
Giant Perineal Condyloma Acuminatum (Buschke-Lowenstein Tumour): A Case Report.巨大会阴性尖锐湿疣(Buschke-Lowenstein肿瘤):一例报告
Chirurgia (Bucur). 2016 Sept-Oct;111(5):435-438. doi: 10.21614/chirurgia.111.5.435.
6
Case report: Buschke-Lowenstein tumor, a giant anal condyloma acuminata.病例报告: Buschke-Lowenstein 肿瘤,巨大肛门尖锐湿疣。
Cir Cir. 2023;91(6):835-838. doi: 10.24875/CIRU.22000302.
7
The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.巨大型尖锐湿疣(Buschke-Lowenstein 肿瘤)的发病机制:概述。
Int J Mol Sci. 2022 Apr 20;23(9):4547. doi: 10.3390/ijms23094547.
8
Perianal giant condyloma acuminatum (Buschke-Löwenstein tumor). Case report and review of the literature.肛周巨大尖锐湿疣(Buschke-Löwenstein瘤)。病例报告及文献复习。
Chirurgia (Bucur). 2011 Jul-Aug;106(4):535-9.
9
[Surgical treatment of a perianal giant condyloma acuminata in a HIV patient].[一名艾滋病患者肛周巨大尖锐湿疣的外科治疗]
Rev Gastroenterol Mex. 2011 Apr-Jun;76(2):178-81.
10
[Buschke-Lowenstein tumor associated with scrotal melanoma. A case report].[与阴囊黑色素瘤相关的Buschke-Lowenstein肿瘤。病例报告]
Prog Urol. 2012 Jan;22(1):70-2. doi: 10.1016/j.purol.2011.02.014. Epub 2011 Apr 20.

本文引用的文献

1
Buschke-Löwenstein tumors: A series of 7 case reports.Buschke-Löwenstein肿瘤:7例病例报告系列
Exp Ther Med. 2022 Jun;23(6):393. doi: 10.3892/etm.2022.11320. Epub 2022 Apr 13.
2
Buschke-Löwenstein tumour: a rare and challenging entity. Buschke-Löwenstein 肿瘤:一种罕见且具有挑战性的实体。
BMJ Case Rep. 2021 Sep 16;14(9):e244192. doi: 10.1136/bcr-2021-244192.
3
[Buschke-Löwenstein´ tumor].[ Buschke-Löwenstein肿瘤]
Pan Afr Med J. 2020 Aug 28;36:359. doi: 10.11604/pamj.2020.36.359.13292. eCollection 2020.
4
Penile carcinoma and HPV infection (Review).阴茎癌与HPV感染(综述)
Exp Ther Med. 2020 Jul;20(1):91-96. doi: 10.3892/etm.2019.8181. Epub 2019 Nov 11.
5
The quadrivalent HPV vaccine is protective against genital warts: a meta-analysis.四价人乳头瘤病毒(HPV)疫苗对预防生殖器疣具有保护作用:一项荟萃分析。
BMC Public Health. 2020 May 28;20(1):691. doi: 10.1186/s12889-020-08753-y.
6
Neoadjuvant chemotherapy and penile conservation in the management of Buschke - Lowenstein tumor, a case report.新辅助化疗与保留阴茎治疗Buschke-Lowenstein肿瘤:一例报告
Urol Case Rep. 2019 Dec 23;29:101111. doi: 10.1016/j.eucr.2019.101111. eCollection 2020 Mar.
7
Giant condyloma acuminatum (Buschke-Lowenstein tumor): Combined treatment with surgery and chemotherapy.巨大尖锐湿疣( Buschke-Lowenstein 肿瘤):手术联合化疗的综合治疗。
Dermatol Ther. 2020 Jan;33(1):e13193. doi: 10.1111/dth.13193. Epub 2019 Dec 23.
8
Clinicopathologic features of Buschke-Löwenstein tumor: a multi-institutional analysis of 38 cases. Buschke-Löwenstein 肿瘤的临床病理特征:38 例多机构分析。
Virchows Arch. 2020 Apr;476(4):543-550. doi: 10.1007/s00428-019-02680-z. Epub 2019 Nov 15.
9
Giant perianal condyloma acuminatum in an infant without sexual abuse.无性虐待史婴儿的巨大肛周尖锐湿疣
Arch Pediatr. 2019 Nov;26(8):473-474. doi: 10.1016/j.arcped.2019.09.003. Epub 2019 Oct 10.
10
Premalignant and Malignant Perianal Lesions.肛管癌前病变与恶性病变
Clin Colon Rectal Surg. 2019 Sep;32(5):386-393. doi: 10.1055/s-0039-1687835. Epub 2019 Aug 22.