• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Structure-mutagenicity relationships of N-oxidized derivatives of aniline, o-toluidine, 2'-methyl-4-aminobiphenyl, and 3,2'-dimethyl-4-aminobiphenyl.

作者信息

Hecht S S, El-Bayoumy K, Tulley L, LaVoie E

出版信息

J Med Chem. 1979 Aug;22(8):981-7. doi: 10.1021/jm00194a019.

DOI:10.1021/jm00194a019
PMID:385878
Abstract
摘要

相似文献

1
Structure-mutagenicity relationships of N-oxidized derivatives of aniline, o-toluidine, 2'-methyl-4-aminobiphenyl, and 3,2'-dimethyl-4-aminobiphenyl.苯胺、邻甲苯胺、2'-甲基-4-氨基联苯和3,2'-二甲基-4-氨基联苯的N-氧化衍生物的结构-致突变性关系。
J Med Chem. 1979 Aug;22(8):981-7. doi: 10.1021/jm00194a019.
2
Mutagenicity of three aromatic amines in the presence of fractions from various tissues.
Toxicol Lett. 1982 May;11(3-4):313-20. doi: 10.1016/0378-4274(82)90166-7.
3
Liver, kidney and small-intestine microsomal-mediated mutagenicity of carcinogenic aromatic amines.
Mutat Res. 1984 Jan;125(1):23-31. doi: 10.1016/0027-5107(84)90028-9.
4
Effect of butylated hydroxytoluene and butylated hydroxyanisole on the mutagenicity of 3,2'-dimethyl-4-aminobiphenyl.丁基化羟基甲苯和丁基化羟基茴香醚对3,2'-二甲基-4-氨基联苯致突变性的影响。
Nutr Cancer. 1983;5(3-4):153-8. doi: 10.1080/01635588309513792.
5
4-Chloromethylbiphenyl (4CMB): a novel mutagen and potential carcinogen.
Carcinogenesis. 1981;2(1):33-8. doi: 10.1093/carcin/2.1.33.
6
Diphenyl ether herbicides and related compounds: structure--activity relationships as bacterial mutagens.二苯醚类除草剂及相关化合物:作为细菌诱变剂的构效关系
J Agric Food Chem. 1983 Nov-Dec;31(6):1201-7. doi: 10.1021/jf00120a015.
7
Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers.共诱变剂去甲哈尔满与邻甲苯胺和间甲苯胺异构体产生的诱变剂结构。
Mutat Res. 2001 Jun 27;493(1-2):115-26. doi: 10.1016/s1383-5718(01)00168-1.
8
Rationally designing safer anilines: the challenging case of 4-aminobiphenyls.合理设计更安全的苯胺:4-氨基联苯的挑战性案例。
J Med Chem. 2012 Apr 26;55(8):3923-33. doi: 10.1021/jm3001295. Epub 2012 Apr 4.
9
Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.人N-乙酰基转移酶和在鼠伤寒沙门氏菌umu测试菌株中表达的细胞色素P450酶将氨基苯基去甲哈尔满、氨基甲基苯基去甲哈尔满和氨基苯基哈尔满激活为基因毒性代谢物。
Mutagenesis. 2006 Nov;21(6):411-6. doi: 10.1093/mutage/gel047. Epub 2006 Oct 25.
10
A rationale for the non-mutagenicity of 2- and 3-aminobiphenyls.
Carcinogenesis. 1989 Aug;10(8):1403-7. doi: 10.1093/carcin/10.8.1403.

引用本文的文献

1
Early detection of urinary bladder carcinogens in rats by immunohistochemistry for γ-H2AX: a review from analyses of 100 chemicals.通过γ-H2AX免疫组织化学早期检测大鼠膀胱致癌物:对100种化学物质分析的综述
J Toxicol Pathol. 2022 Oct;35(4):283-298. doi: 10.1293/tox.2022-0061. Epub 2022 Aug 18.
2
In vivo metabolism of 3,2'-dimethyl-4-aminobiphenyl (DMAB) bearing on its organotropism in the Syrian golden hamster and the F344 rat.3,2'-二甲基-4-氨基联苯(DMAB)在叙利亚金仓鼠和F344大鼠体内的代谢及其对器官亲和性的影响
Environ Health Perspect. 1983 Mar;49:223-31. doi: 10.1289/ehp.8349223.
3
Selective induction of prostate carcinomas in F344 rats treated with intraperitoneal injections of N-hydroxy-3,2'-dimethyl-4-aminobiphenyl.
用腹腔注射N-羟基-3,2'-二甲基-4-氨基联苯处理的F344大鼠中前列腺癌的选择性诱导。
Jpn J Cancer Res. 1990 Apr;81(4):320-3. doi: 10.1111/j.1349-7006.1990.tb02569.x.
4
Dose dependence of N-hydroxy-3,2'-dimethyl-4-aminobiphenyl-induced rat prostate carcinogenesis.N-羟基-3,2'-二甲基-4-氨基联苯诱导大鼠前列腺癌发生的剂量依赖性
Jpn J Cancer Res. 1992 Jul;83(7):695-8. doi: 10.1111/j.1349-7006.1992.tb01968.x.