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Restricted access and advanced disease in post-pandemic testicular cancer.

作者信息

Fagan Mitchell, Janes W C Ian, Andrews Matthew, Harvey David R, Warden Geoff M, Organ Michael K, Johnston Paul

机构信息

Faculty of Medicine, Memorial University, St. John's, NL, Canada.

Department of Urology, Memorial University, St. John's, NL, Canada.

出版信息

Can Urol Assoc J. 2024 Aug;18(8):262-267. doi: 10.5489/cuaj.8648.


DOI:10.5489/cuaj.8648
PMID:38587978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11326728/
Abstract

INTRODUCTION: Urologists observed reduced cancer consultations and surgeries during the SARS-CoV-2 pandemic, raising concern about treatment delays. Testicular cancer serves as a particularly sensitive marker of this phenomenon, as the clinical stage of testicular cancer at presentation is predictive of cancer-specific survival. We aimed to investigate whether COVID-related restrictions to primary care access resulted in increased incidence of metastatic germ cell testis cancer. METHODS: A retrospective chart review was conducted on all cases of testicular cancer managed surgically at our center from March 1, 2018, to February 28, 2023. Patients were categorized into temporal cohorts, representing before, during, and following the implementation of COVID-19 public health restrictions in the province of Newfoundland and Labrador. RESULTS: Forty-one cases of testicular germ cell tumors were identified during the study period. The mean age at diagnosis was 40.8 years (standard deviation ±13.7). Demographics did not vary across the cohorts. Clinical stage 3 disease remained stable before and during the pandemic at 10.5% and 9.1% of cases, respectively. In the post-pandemic period, there was an increase to 27.3% (p=0.617). Surgical wait times remained stable across the pandemic (p=0.151). CONCLUSIONS: There was a 16.8% rise in clinical stage 3 disease from the pre-pandemic to post-pandemic period. Our study failed to identify a statistically significant increase in metastatic testis cancer incidence upon lifting of pandemic restrictions. Further study is necessary to confirm suspicions that pandemic restrictions contributed to increased incidence of metastatic testis cancer.

摘要

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本文引用的文献

[1]
Stage migration of testicular germ cell tumours in Alberta, Canada, during the COVID-19 pandemic: a retrospective cohort study.

CMAJ Open. 2022

[2]
Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study.

Am J Obstet Gynecol. 2022-11

[3]
Canadian Urological Association consensus guideline: Management of testicular germ cell cancer.

Can Urol Assoc J. 2022-6

[4]
COVID-19 pandemic impact on uro-oncological disease outcomes at an Italian tertiary referral center.

World J Urol. 2022-1

[5]
Measuring the impact of the COVID-19 pandemic on organized cancer screening and diagnostic follow-up care in Ontario, Canada: A provincial, population-based study.

Prev Med. 2021-10

[6]
Applicability of COVID-19 Pandemic Recommendations for Urology Practice: Data from Three Major Italian Hot Spots (BreBeMi).

Eur Urol Open Sci. 2021-4

[7]
Impact of SARS-CoV-2 Pandemic on Colorectal Cancer Screening Delay: Effect on Stage Shift and Increased Mortality.

Clin Gastroenterol Hepatol. 2021-7

[8]
Delaying Cancer Cases in Urology during COVID-19: Review of the Literature.

J Urol. 2020-7-25

[9]
Testicular Cancer: Diagnosis and Treatment.

Am Fam Physician. 2018-2-15

[10]
Outcome of Critically Ill Patients with Testicular Cancer.

Biomed Res Int. 2017-10-26

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