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先天性胆脂瘤的流行病学:日本过去17年的调查

Epidemiology of Congenital Cholesteatoma: Surveys of the Last 17 Years in Japan.

作者信息

Kadowaki Yoshinori, Ide Shinsuke, Nakamura Takeshi, Okuda Takumi, Shigemi Hideto, Hirano Takashi, Takahashi Kuniyuki, Suzuki Masashi

机构信息

Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Oita University, Oita 879-5593, Japan.

Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, Miyazaki University, Miyazaki 889-1601, Japan.

出版信息

J Clin Med. 2024 Feb 23;13(5):1276. doi: 10.3390/jcm13051276.

DOI:10.3390/jcm13051276
PMID:38592124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10931836/
Abstract

(1) : The incidence of congenital cholesteatoma (CC) has rarely been discussed, particularly from a demographic viewpoint. Therefore, we conducted an epidemiological study of CC using local medical characteristics. (2) : The participants were 100 patients (101 ears) who underwent initial surgical treatment at university hospitals in two rural prefectures between 2006 and 2022. A total of 68% of the patients were males and 32% were females, with a median age of 5 years. We reviewed the medical records for the date of birth, date of surgery, stage of disease, and first symptoms of the disease. (3) : The total incidence of CC was calculated to be 26.44 per 100,000 births and tended to increase. No significant difference was found between the incidences in the two prefectures. The number of surgeries performed was higher in the second half of the study period. No difference in the stage of progress was observed based on age. (4) : The incidence of CC was estimated to be 26.44 per 100,000 newborn births. The number of patients with CC tended to increase; however, this can be attributed to an increase in the detection rate rather than the incidence.

摘要

(1):先天性胆脂瘤(CC)的发病率很少被讨论,尤其是从人口统计学角度。因此,我们利用当地医疗特征对CC进行了一项流行病学研究。(2):研究对象为2006年至2022年间在两个农村县的大学医院接受初次手术治疗的100例患者(101只耳朵)。患者中68%为男性,32%为女性,中位年龄为5岁。我们查阅了病历,以获取出生日期、手术日期、疾病分期和疾病的首发症状。(3):CC的总发病率经计算为每10万例出生中有26.44例,且呈上升趋势。两个县的发病率之间未发现显著差异。在研究期的后半段进行的手术数量更多。未观察到基于年龄的病情进展阶段差异。(4):CC的发病率估计为每10万例新生儿中有26.44例。CC患者的数量呈上升趋势;然而,这可能归因于检出率的增加而非发病率的上升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/f46213da6ddc/jcm-13-01276-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/d4880da5c055/jcm-13-01276-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/3111bd24bbe4/jcm-13-01276-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/d9d375cce066/jcm-13-01276-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/d430ef004c40/jcm-13-01276-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/f46213da6ddc/jcm-13-01276-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/d4880da5c055/jcm-13-01276-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/3111bd24bbe4/jcm-13-01276-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/d9d375cce066/jcm-13-01276-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/d430ef004c40/jcm-13-01276-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5491/10931836/f46213da6ddc/jcm-13-01276-g003.jpg

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本文引用的文献

1
A Case of a Congenital Cholesteatoma Without Growth for a Long Term.一例长期无生长的先天性胆脂瘤病例。
Cureus. 2023 Jun 25;15(6):e40945. doi: 10.7759/cureus.40945. eCollection 2023 Jun.
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Congenital cholesteatoma clinical and surgical management.先天性胆脂瘤的临床与外科治疗
Int J Pediatr Otorhinolaryngol. 2023 Jan;164:111401. doi: 10.1016/j.ijporl.2022.111401. Epub 2022 Dec 8.
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Nationwide survey of middle ear cholesteatoma surgery cases in Japan: Results from the Japan Otological society registry using the JOS staging and classification system.
日本全国中耳胆脂瘤手术病例调查:日本耳科学会登记处采用JOS分期和分类系统的结果。
Auris Nasus Larynx. 2021 Aug;48(4):555-564. doi: 10.1016/j.anl.2020.09.011. Epub 2020 Sep 25.
4
Malformations Associated With Pediatric Congenital Cholesteatomas.小儿先天性胆脂瘤相关畸形。
Otol Neurotol. 2020 Oct;41(9):e1128-e1132. doi: 10.1097/MAO.0000000000002761.
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Rate of chronic otitis media operations and cholesteatoma surgeries in South Korea: a nationwide population-based study (2006-2018).韩国慢性中耳炎手术和胆脂瘤手术的发生率:一项全国性基于人群的研究(2006-2018 年)。
Sci Rep. 2020 Jul 9;10(1):11356. doi: 10.1038/s41598-020-67799-5.
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Middle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis.中耳先天性胆脂瘤:系统评价、荟萃分析及其发病机制的探讨。
Eur Arch Otorhinolaryngol. 2020 Apr;277(4):987-998. doi: 10.1007/s00405-020-05792-4. Epub 2020 Jan 18.
7
International Pediatric Otolaryngology Group (IPOG) Consensus Recommendations: Congenital Cholesteatoma.国际小儿耳鼻喉科学组(IPOG)共识建议:先天性胆脂瘤。
Otol Neurotol. 2020 Mar;41(3):345-351. doi: 10.1097/MAO.0000000000002521.
8
Nationwide survey of congenital cholesteatoma using staging and classification criteria for middle ear cholesteatoma proposed by the Japan Otological Society.使用日本耳科学会提出的中耳胆脂瘤分期和分类标准对先天性胆脂瘤进行全国性调查。
Auris Nasus Larynx. 2019 Jun;46(3):346-352. doi: 10.1016/j.anl.2018.10.015. Epub 2018 Nov 8.
9
EAONO/JOS Joint Consensus Statements on the Definitions, Classification and Staging of Middle Ear Cholesteatoma.欧洲耳鼻咽喉头颈外科学会/日本耳科学会关于中耳胆脂瘤定义、分类及分期的联合共识声明
J Int Adv Otol. 2017 Apr;13(1):1-8. doi: 10.5152/iao.2017.3363. Epub 2017 Jan 6.
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