化疗和放疗后肌肉松弛剂的使用
The Use of Muscle Relaxants After Chemotherapy and Radiotherapy.
作者信息
Radkowski Paweł, Jacewicz Michał, Podlińska Iwona, Derkaczew Maria
机构信息
Department of Anaesthesiology and Intensive Care, Regional Specialist Hospital in Olsztyn, Olsztyn, Poland.
Department of Anaesthesiology and Intensive Care, Faculty of Medicine, Collegium Medicum University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
出版信息
Int J Gen Med. 2024 Apr 4;17:1349-1354. doi: 10.2147/IJGM.S452999. eCollection 2024.
INTRODUCTION
Patients after chemotherapy and radiotherapy while being operated can suffer from different systemic problems, which may complicate the anesthetic management. Some interactions between muscle relaxants and chemotherapeutics can occur.
AIM
This article aims to present the use of muscle relaxants in cancer patients who have undergone chemotherapy and radiotherapy.
MATERIAL AND METHODS
Our work is based on the available literature and the authors' experience.
CONCLUSION
Based on our observations and a thorough examination of the medical literature, it is advisable to exercise significant caution when employing muscle relaxants in individuals undergoing chemotherapy and radiotherapy. All muscle relaxants can behave differently after chemotherapy and radiotherapy, and for this reason, practitioners should familiarize themselves with the pharmacodynamics and pharmacokinetics of their chosen muscle relaxant.
引言
接受化疗和放疗后的患者在手术时可能会出现不同的全身问题，这可能会使麻醉管理复杂化。肌肉松弛剂与化疗药物之间可能会发生一些相互作用。
目的
本文旨在介绍肌肉松弛剂在接受过化疗和放疗的癌症患者中的应用。
材料与方法
我们的工作基于现有文献和作者的经验。
结论
根据我们的观察以及对医学文献的全面审查，在对接受化疗和放疗的患者使用肌肉松弛剂时应格外谨慎。所有肌肉松弛剂在化疗和放疗后的表现可能会有所不同，因此，从业者应熟悉所选肌肉松弛剂的药效学和药代动力学。
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