Sarabia Ochoa Rosalía, García de la Torre Juan Pablo
Servicio de Anatomía Patológica, Hospital General Universitario de Albacete, Albacete, España.
Servicio de Anatomía Patológica, Hospital General Universitario de Albacete, Albacete, España.
Rev Esp Patol. 2024 Apr-Jun;57(2):146-150. doi: 10.1016/j.patol.2024.01.002. Epub 2024 Feb 12.
Spermatocytic tumor is a very rare germ cell testicular neoplasm that accounts for less than 1% of testicular cancers. It generally affects older men with a mean age of 53.6 years (range 19-92 years). Spermatocytic tumor is classified within the group of germ cell tumors not related to germ cell neoplasia in situ. It presents clinicopathological characteristics different from classic seminoma and is not considered a variant of the latter. Due to a morphologic overlap with classical seminoma, it was called "sperm cell seminoma" in the past. The anaplastic variant of spermatocytic tumor is exceptional, few cases have been described in the literature, it presents an earlier onset compared to spermatocytic tumor and a benign behavior despite showing histological patterns similar to classic seminoma. We present the second case of bilateral synchronous anaplastic spermatocytic tumor, in a young patient treated with orchiectomy and chemotherapy.
精母细胞瘤是一种非常罕见的睾丸生殖细胞肿瘤,占睾丸癌的比例不到1%。它通常影响老年男性,平均年龄为53.6岁(范围19 - 92岁)。精母细胞瘤归类于与原位生殖细胞肿瘤无关的生殖细胞肿瘤组。它呈现出与经典精原细胞瘤不同的临床病理特征,不被认为是后者的变体。由于与经典精原细胞瘤在形态学上有重叠,过去它被称为“精子细胞性精原细胞瘤”。精母细胞瘤的间变性变体很罕见,文献中描述的病例很少,它与精母细胞瘤相比发病较早,尽管显示出与经典精原细胞瘤相似的组织学模式,但行为良性。我们报告了第二例双侧同步性间变性精母细胞瘤病例,该病例为一名接受睾丸切除术和化疗的年轻患者。