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Management of potentially inappropriate medication use among older adult's patients in primary care settings: description of an interventional prospective non-randomized study.基层医疗中老年患者潜在不适当药物使用的管理:一项干预性前瞻性非随机研究的描述。
BMC Prim Care. 2024 Jun 13;25(1):213. doi: 10.1186/s12875-024-02334-3.
2
The MGPIDP-L project: Potentially inappropriate drug prescribing and its associated factors.MGPIDP-L项目:潜在不适当用药及其相关因素。
Arch Gerontol Geriatr. 2023 Jun;109:104947. doi: 10.1016/j.archger.2023.104947. Epub 2023 Jan 28.
3
Global prevalence of falls in the older adults: a comprehensive systematic review and meta-analysis.全球老年人跌倒的患病率:全面的系统评价和荟萃分析。
J Orthop Surg Res. 2022 Jun 28;17(1):334. doi: 10.1186/s13018-022-03222-1.
4
Impact of pharmacist-led interventions on patient care in ambulatory care settings: A systematic review.药剂师主导的干预措施对门诊环境中患者护理的影响:系统评价。
Int J Clin Pract. 2021 Nov;75(11):e14864. doi: 10.1111/ijcp.14864. Epub 2021 Sep 20.
5
Medication Review in Preventing Older Adults' Fall-Related Injury: a Systematic Review & Meta-Analysis.药物审查预防老年人跌倒相关伤害:一项系统评价与荟萃分析
Can Geriatr J. 2021 Sep 1;24(3):237-250. doi: 10.5770/cgj.24.478. eCollection 2021 Sep.
6
Fall Risk-Increasing Drugs, Polypharmacy, and Falls Among Low-Income Community-Dwelling Older Adults.增加跌倒风险的药物、多重用药与低收入社区居住老年人的跌倒情况
Innov Aging. 2021 Jan 8;5(1):igab001. doi: 10.1093/geroni/igab001. eCollection 2021.
7
Deprescribing fall-risk increasing drugs (FRIDs) for the prevention of falls and fall-related complications: a systematic review and meta-analysis.停用增加跌倒风险的药物(FRIDs)以预防跌倒及跌倒相关并发症:一项系统评价与荟萃分析
BMJ Open. 2021 Feb 10;11(2):e035978. doi: 10.1136/bmjopen-2019-035978.
8
Fall related injuries in elderly patients in a tertiary care centre in Beirut, Lebanon.黎巴嫩贝鲁特一家三级护理中心老年患者的跌倒相关损伤
J Emerg Trauma Shock. 2020 Apr-Jun;13(2):142-145. doi: 10.4103/JETS.JETS_84_19. Epub 2020 Jun 10.
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Falls and risk factors of falls for urban and rural community-dwelling older adults in China.中国城乡社区老年人跌倒及其危险因素。
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Ther Adv Drug Saf. 2019 Sep 27;10:2042098619868640. doi: 10.1177/2042098619868640. eCollection 2019.

多药物治疗的老年黎巴嫩患者在初级保健环境中的跌倒风险因素:“MGPIDP-L 项目”的二次横断面分析。

Fall risk factors among poly-medicated older Lebanese patients in primary care settings: a secondary cross-sectional analysis of the "MGPIDP-L project".

机构信息

Paul Sabatier University III, 31063, Toulouse, France.

Aging and Research Team, Center for Epidemiology and Research in POPulation Health (CERPOP), Toulouse University, Inserm, Paul Sabatier University, Faculty of Medecine, 37 Allées J.Guesde, 31000, Toulouse, France.

出版信息

BMC Geriatr. 2024 Apr 10;24(1):327. doi: 10.1186/s12877-024-04951-0.

DOI:10.1186/s12877-024-04951-0
PMID:38600461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11008041/
Abstract

BACKGROUND

Falling is a major concern for the health of older adults and significantly affects their quality of life. Identifying the various risk factors and the differences between older patients can be challenging. The objective of this study was to identify the risk factors for falls among polymedicated community-dwelling older Lebanese patients following a medication review.

METHODS

In this analytical cross-sectional study, we examined the risk factors for falls in 850 patients aged ≥ 65 years who were taking ≥ 5 medications daily. The study involved conducting a medication review over the course of a year in primary care settings and using multivariate logistic regression analysis to analyze the data.

RESULTS

Our results showed that 106 (19.5%) of the 850 included patients had fallen at least once in the three months prior to the medication review. Loss of appetite and functional dependence were identified as the most significant predictors of falls ORa = 3.020, CI [2.074-4.397] and ORa = 2.877, CI [1.787-4.632], respectively. Other risk factors for falls included drowsiness ORa = 2.172, CI [1.499-3.145], and the use of beta-blockers ORa = 1.943, CI [1.339-2.820].

CONCLUSION

Our study highlights the importance of addressing multiple risk factors for falls among Lebanese older adults and emphasizes the need for customized interventions and ongoing monitoring to prevent falls and improve health outcomes. This study sheds light on a critical issue in the Lebanese older population and provides valuable insight into the complex nature of falls among poly-medicated Lebanese community-dwelling older adults.

TRIAL REGISTRATION

2021REC-001- INSPECT -09-04.

摘要

背景

跌倒对老年人的健康是一个主要关注点,并且会显著影响他们的生活质量。识别各种风险因素以及老年患者之间的差异可能具有挑战性。本研究的目的是在对药物进行审查后,确定服用多种药物的社区居住的黎巴嫩老年患者跌倒的风险因素。

方法

在这项分析性横断面研究中,我们检查了 850 名年龄≥65 岁且每天服用≥5 种药物的患者跌倒的风险因素。该研究涉及在初级保健环境中进行为期一年的药物审查,并使用多变量逻辑回归分析来分析数据。

结果

我们的结果表明,在药物审查前三个月内,850 名纳入患者中有 106 名(19.5%)至少跌倒过一次。食欲不振和功能依赖被确定为跌倒的最显著预测因素,ORa=3.020,CI [2.074-4.397] 和 ORa=2.877,CI [1.787-4.632]。其他跌倒风险因素包括嗜睡 ORa=2.172,CI [1.499-3.145] 和使用β受体阻滞剂 ORa=1.943,CI [1.339-2.820]。

结论

我们的研究强调了针对黎巴嫩老年患者跌倒的多个风险因素进行干预的重要性,并强调需要进行个性化干预和持续监测,以预防跌倒和改善健康结果。本研究揭示了黎巴嫩老年人群中的一个关键问题,并为服用多种药物的黎巴嫩社区居住的老年患者中跌倒的复杂性提供了有价值的见解。

试验注册

2021REC-001-INSPECT-09-04。