College of Pharmacy, Jiamusi University, Jiamusi, Heilongjiang, China.
Heilongjiang Pharmaceutical Research Institute, Jiamusi, Heilongjiang, China.
Front Endocrinol (Lausanne). 2024 Mar 27;15:1308016. doi: 10.3389/fendo.2024.1308016. eCollection 2024.
In recent years, with the improvement of people's living standards, the incidence of DM has increased year by year in China. DM is a common metabolic syndrome characterized by hyperglycemia caused by genetic, environmental and other factors. At the same time, long-term suffering from DM will also have an impact on the heart, blood vessels, eyes, kidneys and nerves, and associated serious diseases. The human body has a large and complex gut microbiota, which has a significant impact on the body's metabolism. Research shows that the occurrence and development of DM and its complications are closely related to intestinal microbiota. At present, western medicine generally treats DM with drugs. The hypoglycemic effect is fast and strong, but it can have a series of side effects on the human body. Compared with western medicine, Chinese medicine has its unique views and methods in treating DM. TCM can improve symptoms and treat complications by improving the imbalance of microbiota in patients with DM. Its characteristics of health, safety, and reliability are widely accepted by the general public. This article reviews the relationship between intestinal microbiota and DM, as well as the mechanism of TCM intervention in DM by regulating intestinal microbiota.
近年来，随着人们生活水平的提高，中国的糖尿病（DM）发病率逐年上升。DM 是一种常见的代谢综合征，其特征是由遗传、环境等多种因素引起的高血糖。同时，长期患有 DM 还会对心脏、血管、眼睛、肾脏和神经造成影响，并伴有严重的并发症。人体拥有庞大而复杂的肠道微生物群，其对人体的新陈代谢有着显著的影响。研究表明，DM 的发生和发展及其并发症与肠道微生物群密切相关。目前，西医一般采用药物治疗 DM，降糖作用迅速而强大，但会对人体产生一系列副作用。与西医相比，中医在治疗 DM 方面有其独特的观点和方法。中医可以通过改善 DM 患者肠道微生物群的失衡来改善症状并治疗并发症。其具有健康、安全、可靠的特点，被广大民众所接受。本文综述了肠道微生物群与 DM 的关系，以及通过调节肠道微生物群来干预 DM 的中医机制。
