• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

腹腔镜根治性全胃切除术联合胰脾切除术治疗胃和胰腺同步癌

Laparoscopic Radical Total Gastrectomy and Pancreatosplenectomy for Synchronous Cancer of the Stomach and Pancreas.

作者信息

Ebihara Motoki, Fujisawa Kentoku, Haruta Shusuke, Uruga Hironori, Ueno Masaki

机构信息

Department of Gastroenterological Surgery, Toranomon Hospital, Tokyo, JPN.

Department of Pathology, Toranomon Hospital, Tokyo, JPN.

出版信息

Cureus. 2024 Mar 11;16(3):e55927. doi: 10.7759/cureus.55927. eCollection 2024 Mar.

DOI:10.7759/cureus.55927
PMID:38601428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11004720/
Abstract

The safety of laparoscopic surgery for advanced gastric and pancreatic cancers has been established individually, but there is little evidence for synchronous cancers. In this case, a 59-year-old man with a history of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) treatment for diffuse large B-cell lymphoma underwent laparoscopic surgery for a suspected pancreatic invasion of advanced gastric cancer. Pathology revealed double cancer of the stomach and pancreas. Laparoscopic total gastrectomy and distal pancreatectomy were successfully performed. The patient had a pancreatic leak on postoperative day seven but was discharged from the hospital on postoperative day 21. This case suggests the possibility of expanding the indications for laparoscopic surgery for similar cancers in the future. Additionally, the anatomical reticulum can be resected as a single mass using laparoscopy alone.

摘要

腹腔镜手术用于晚期胃癌和胰腺癌的安全性已分别得到证实，但对于同时性癌的证据却很少。在此病例中，一名59岁男性，有因弥漫性大B细胞淋巴瘤接受R-CHOP（利妥昔单抗、环磷酰胺、多柔比星、长春新碱和泼尼松龙）治疗的病史，因怀疑晚期胃癌侵犯胰腺而接受了腹腔镜手术。病理检查发现胃和胰腺双原发癌。成功实施了腹腔镜全胃切除术和远端胰腺切除术。患者术后第7天出现胰瘘，但术后第21天出院。该病例提示未来有可能扩大腹腔镜手术用于类似癌症的适应证。此外，利用腹腔镜单独操作可将解剖学上的网膜作为一个整体切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/08696bef92fa/cureus-0016-00000055927-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/17dcdca6369b/cureus-0016-00000055927-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/af356097ec55/cureus-0016-00000055927-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/e6dbce840869/cureus-0016-00000055927-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/b8e8fade3f90/cureus-0016-00000055927-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/42ff587bf637/cureus-0016-00000055927-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/25f63b2a7bf8/cureus-0016-00000055927-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/ad348b31e712/cureus-0016-00000055927-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/08696bef92fa/cureus-0016-00000055927-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/17dcdca6369b/cureus-0016-00000055927-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/af356097ec55/cureus-0016-00000055927-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/e6dbce840869/cureus-0016-00000055927-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/b8e8fade3f90/cureus-0016-00000055927-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/42ff587bf637/cureus-0016-00000055927-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/25f63b2a7bf8/cureus-0016-00000055927-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/ad348b31e712/cureus-0016-00000055927-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc70/11004720/08696bef92fa/cureus-0016-00000055927-i08.jpg

相似文献

1
Laparoscopic Radical Total Gastrectomy and Pancreatosplenectomy for Synchronous Cancer of the Stomach and Pancreas.腹腔镜根治性全胃切除术联合胰脾切除术治疗胃和胰腺同步癌
Cureus. 2024 Mar 11;16(3):e55927. doi: 10.7759/cureus.55927. eCollection 2024 Mar.
2
Laparoscopic radical antegrade modular pancreatosplenectomy for left-sided pancreatic cancer using the ligament of Treitz approach.经屈氏韧带入路腹腔镜根治性顺行模块化胰脾切除术治疗左侧胰腺癌。
Surg Endosc. 2017 Nov;31(11):4836-4837. doi: 10.1007/s00464-017-5561-6. Epub 2017 Apr 13.
3
[Feasibility, safety and long-term efficacy of laparoscopic total gastrectomy combined with distal pancreaticosplenectomy for T4b gastric cancer].腹腔镜全胃切除术联合远端胰腺脾切除术治疗T4b期胃癌的可行性、安全性及长期疗效
Zhonghua Wei Chang Wai Ke Za Zhi. 2020 Feb 25;23(2):163-169. doi: 10.3760/cma.j.issn.1671-0274.2020.02.012.
4
Totally laparoscopic complete bursectomy and D2 lymphadenectomy in radical total gastrectomy: an outside bursa omentalis approach.全腹腔镜根治性全胃切除术中完全网膜囊切除术及D2淋巴结清扫术：一种网膜囊外入路
Surg Endosc. 2016 Sep;30(9):4152. doi: 10.1007/s00464-015-4702-z. Epub 2015 Dec 16.
5
Feasibility and Safety of Laparoscopic Radical Distal Pancreatosplenectomy with Adrenalectomy in Advanced Pancreatic Cancer.腹腔镜根治性远端胰腺脾切除术联合肾上腺切除术治疗晚期胰腺癌的可行性和安全性。
Ann Surg Oncol. 2020 Dec;27(13):5235-5236. doi: 10.1245/s10434-020-08670-9. Epub 2020 May 31.
6
[Real-world data analysis of 3012 patients undergoing laparoscopic radical gastrectomy in a single center over the past 12 years].[对过去12年在单一中心接受腹腔镜根治性胃切除术的3012例患者的真实世界数据分析]
Zhonghua Wei Chang Wai Ke Za Zhi. 2022 Aug 25;25(8):716-725. doi: 10.3760/cma.j.cn441530-20220613-00257.
7
Laparoscopic D2 total gastrectomy and en-mass splenectomy and distal pancreatectomy for locally advanced proximal gastric cancer.腹腔镜 D2 全胃切除术、脾切除术和胰体尾切除术治疗局部进展期近端胃癌。
Surg Endosc. 2018 Apr;32(4):2156. doi: 10.1007/s00464-017-5801-9. Epub 2017 Aug 25.
8
Laparoscopic subtotal pancreatectomy with radical antegrade modular pancreatosplenectomy for left-sided pancreatic cancer.腹腔镜下全胰次全切除术联合根治性顺行模块化胰脾切除术治疗左侧胰腺癌
Surg Oncol. 2019 Mar;28:150. doi: 10.1016/j.suronc.2018.12.006. Epub 2019 Jan 3.
9
Laparoscopic distal pancreatosplenectomy for left-sided pancreatic cancer in patients with radical subtotal gastrectomy for gastric cancer.腹腔镜下远端胰腺脾切除术治疗因胃癌行根治性胃大部切除术的左侧胰腺癌患者。
Ann Hepatobiliary Pancreat Surg. 2022 Nov 30;26(4):395-400. doi: 10.14701/ahbps.22-016. Epub 2022 Aug 22.
10
Laparoscopic splenic vessel-preserving distal pancreatectomy after laparoscopic pylorus-preserving gastrectomy: A case report.腹腔镜保留幽门的胃切除术后腹腔镜脾血管保留胰体尾部切除术：一例报告。
Asian J Endosc Surg. 2022 Oct;15(4):859-862. doi: 10.1111/ases.13097. Epub 2022 Jun 16.

引用本文的文献

1
Case Report: Synchronous pancreatic sarcomatoid carcinoma and gastric cancer: a case study with literature review.病例报告：同步性胰腺肉瘤样癌和胃癌：一项文献复习的病例研究
Front Immunol. 2025 May 27;16:1584504. doi: 10.3389/fimmu.2025.1584504. eCollection 2025.
2
A Case of Simultaneous Overlapping Cancer of the Pancreatic Head and Gastric Body Managed With Pancreaticoduodenectomy and Total Gastrectomy in Two Stages.一例胰头和胃体同时性重叠癌分两期行胰十二指肠切除术和全胃切除术治疗的病例
Cureus. 2025 May 9;17(5):e83777. doi: 10.7759/cureus.83777. eCollection 2025 May.

本文引用的文献

1
Minimally invasive versus open distal pancreatectomy for resectable pancreatic cancer (DIPLOMA): an international randomised non-inferiority trial.微创与开放远端胰腺切除术治疗可切除胰腺癌（DIPLOMA）：一项国际随机非劣效性试验
Lancet Reg Health Eur. 2023 Jul 6;31:100673. doi: 10.1016/j.lanepe.2023.100673. eCollection 2023 Aug.
2
Five-Year Survival Outcomes of Laparoscopy-Assisted vs Open Distal Gastrectomy for Advanced Gastric Cancer: The JLSSG0901 Randomized Clinical Trial.腹腔镜辅助与开腹远端胃癌根治术治疗进展期胃癌的 5 年生存结局：JLSSG0901 随机临床试验。
JAMA Surg. 2023 May 1;158(5):445-454. doi: 10.1001/jamasurg.2023.0096.
3
Comparison of safety and effectiveness between laparoscopic and open pancreatoduodenectomy: A systematic review and meta-analysis.
腹腔镜与开腹胰十二指肠切除术的安全性和有效性比较：系统评价和荟萃分析。
Int J Surg. 2022 Sep;105:106799. doi: 10.1016/j.ijsu.2022.106799. Epub 2022 Aug 19.
4
Laparoscopic versus open gastrectomy for gastric cancer: A systematic review and meta-analysis of randomized controlled trials.腹腔镜与开腹胃癌根治术的比较：一项随机对照试验的系统评价和荟萃分析。
Int J Surg. 2022 Jun;102:106678. doi: 10.1016/j.ijsu.2022.106678. Epub 2022 May 16.
5
Laparoscopic Versus Open Gastrectomy for Gastric Cancer (LOGICA): A Multicenter Randomized Clinical Trial.腹腔镜与开腹胃癌根治术（LOGICA）：多中心随机临床试验。
J Clin Oncol. 2021 Mar 20;39(9):978-989. doi: 10.1200/JCO.20.01540. Epub 2021 Jan 6.
6
Safety and Efficacy of Laparoscopic Versus Open Gastrectomy in Patients With Advanced Gastric Cancer Following Neoadjuvant Chemotherapy: A Meta-Analysis.新辅助化疗后进展期胃癌患者腹腔镜与开腹胃切除术的安全性和有效性：一项Meta分析
Front Oncol. 2021 Aug 6;11:704244. doi: 10.3389/fonc.2021.704244. eCollection 2021.
7
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020：全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
8
Long-Term Outcomes of Laparoscopic versus Open Total Gastrectomy for Advanced Gastric Cancer: A Propensity Score-Matched Analysis.腹腔镜与开腹全胃切除术治疗进展期胃癌的长期疗效：倾向评分匹配分析。
Dig Surg. 2020;37(3):220-228. doi: 10.1159/000501427. Epub 2019 Jul 3.
9
Universalization of the operative strategy by systematic mesogastric excision for stomach cancer with that for total mesorectal excision and complete mesocolic excision colorectal counterparts.通过系统的胃系膜切除术将胃癌的手术策略推广至与直肠癌的全直肠系膜切除术和结肠癌的完整结肠系膜切除术相对应的情况。
Ann Gastroenterol Surg. 2017 Oct 23;2(1):28-36. doi: 10.1002/ags3.12048. eCollection 2018 Jan.
10
Prognosis of Pancreatic Cancer Patients with Synchronous or Metachronous Malignancies from Other Organs Is Better than Those with Pancreatic Cancer Only.患有其他器官同步或异时性恶性肿瘤的胰腺癌患者的预后要好于仅患有胰腺癌的患者。
Cancer Res Treat. 2018 Oct;50(4):1175-1185. doi: 10.4143/crt.2017.494. Epub 2017 Dec 20.