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用于提高化疗药物疗效的自愈合水凝胶:抗肉瘤和癌治疗的进展及临床试验可行性

Self-healing hydrogels for enhancing chemotherapy drug efficacy: Advancements in anti-sarcoma and carcinoma therapies and clinical trial feasibility.

作者信息

Taylor Luc

机构信息

Cerebrovascular Health, Exercise, and Environmental Research Sciences (CHEERS) Laboratory, Department of Exercise Science, Physical and Health Education, Faculty of Education, University of Victoria, Victoria, BC V8W 2Y2, Canada.

出版信息

Cancer Pathog Ther. 2024 Feb 2;2(2):132-134. doi: 10.1016/j.cpt.2024.01.003. eCollection 2024 Apr.

DOI:10.1016/j.cpt.2024.01.003
PMID:38601480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11002744/
Abstract

•Site-specific administration is key for optimizing anticancer drug administration; self-healing hydrogels may allow this at reasonable costs and reproducibility.•Self-healing hydrogels have several real-world therapeutic applications, including drug administration.•Self-healing hydrogels are yet to be utilized for chemotherapy drug administration in clinical trials.•Clinical research on using self-healing hydrogels in anticancer therapeutics is feasible and valid compared to other advances in anticancer drug administration.

摘要

•特定部位给药是优化抗癌药物给药的关键;自修复水凝胶可能以合理的成本和可重复性实现这一点。

•自修复水凝胶有多种实际治疗应用,包括药物给药。

•自修复水凝胶尚未在临床试验中用于化疗药物给药。

•与抗癌药物给药的其他进展相比,使用自修复水凝胶进行抗癌治疗的临床研究是可行且有效的。

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本文引用的文献

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miR-338-3p acts as a tumor suppressor in lung squamous cell carcinoma by targeting .miR-338-3p通过靶向……在肺鳞状细胞癌中发挥肿瘤抑制作用。
Cancer Pathog Ther. 2022 Dec 28;1(2):87-97. doi: 10.1016/j.cpt.2022.12.004. eCollection 2023 Apr.
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Carboxymethylcellulose based self-healing hydrogel with coupled DOX as Camptothecin loading carrier for synergetic colon cancer treatment.载多柔比星的羧甲基纤维素基自修复水凝胶作为喜树碱的联合载药体系用于协同结肠癌治疗。
Int J Biol Macromol. 2023 Sep 30;249:126012. doi: 10.1016/j.ijbiomac.2023.126012. Epub 2023 Jul 29.
3
Biomechanical Behaviors and Degradation Properties of Multilayered Polymer Scaffolds: The Phase Space Method for Bile Duct Design and Bioengineering.多层聚合物支架的生物力学行为与降解特性:胆管设计与生物工程的相空间方法
Biomedicines. 2023 Mar 1;11(3):745. doi: 10.3390/biomedicines11030745.
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Cellulose based self-healing hydrogel through Boronic Ester connections for wound healing and antitumor applications.基于纤维素的自修复水凝胶通过硼酸酯键用于伤口愈合和抗肿瘤应用。
Int J Biol Macromol. 2023 Mar 1;230:123294. doi: 10.1016/j.ijbiomac.2023.123294. Epub 2023 Jan 14.
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Self-Healing Hydrogels: Development, Biomedical Applications, and Challenges.自愈水凝胶:发展、生物医学应用及挑战
Polymers (Basel). 2022 Oct 26;14(21):4539. doi: 10.3390/polym14214539.
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The diagnosis, classification, and treatment of sarcoma in this era of artificial intelligence and immunotherapy.肉瘤的诊断、分类和治疗:人工智能和免疫治疗时代。
Cancer Commun (Lond). 2022 Dec;42(12):1288-1313. doi: 10.1002/cac2.12373. Epub 2022 Oct 19.
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Hepatocellular carcinoma.肝细胞癌
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Theranostics. 2022 Feb 7;12(5):2115-2132. doi: 10.7150/thno.69424. eCollection 2022.
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