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黎巴嫩使用精神药物的患者在新冠疫情期间使用仿制药情况:推广仿制药的一个契机

Generic drugs use during the COVID-19 pandemic among Lebanese patients using psychotropics: An opportunity for generic drug promotion.

作者信息

Hatem Georges, Ankouni Ali, Salhab Sethrida, Kteich Walaa, Awada Sanaa

机构信息

Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Hadat, Lebanon.

Faculty of Medicine, University of Porto, Porto, Portugal.

出版信息

J Generic Med. 2023 Jun;19(2):92-100. doi: 10.1177/17411343231162561. Epub 2023 Mar 8.

Abstract

INTRODUCTION

The Coronavirus disease of 2019 (COVID-19) pandemic has imposed several challenges leading to the shortage of medications due to the disruption of their supply chains. Among others, patients using psychotropics encountered difficulties finding their medication despite the efforts of investing in local production. Encouraging patients to use generic drugs can be an effective strategy to ensure sustainable access to medication.

OBJECTIVES

This study aimed to describe the consumption of psychotropic medications during the COVID-19 pandemic and the willingness together with the reasons for using generic drugs. It also assessed the association between generic drugs and the general characteristics of the patients.

DESIGN

A cross-sectional study was performed over a period of 4 months (July-October 2021) targeting 128 patients using psychotropic drugs.

RESULTS

The sample included more women than men with a mean age of 38 years. Antidepressants were the psychotropic medications mostly consumed followed by anti-anxiety medications. Almost 13% of the patients started using psychotropics either through self-prescription or a friend's advice and 73.4% used generic drugs. Fear of dependence, unavailability of the brand drug, and pharmacist's recommendation were the main reported reasons for using generic drugs.

CONCLUSION

During the COVID-19 pandemic, the consumption of psychotropics increased due to new prescriptions and self-medication. No differences were noted between using generics and the characteristics of the patients in contrast to previous studies which support the implementation of generic prescription and substitution policies.

摘要

引言

2019年冠状病毒病(COVID-19)大流行带来了诸多挑战,导致药品供应链中断,药品短缺。其中,使用精神药物的患者尽管在当地生产方面投入了努力,但仍难以找到他们的药物。鼓励患者使用仿制药可能是确保可持续获得药物的有效策略。

目的

本研究旨在描述COVID-19大流行期间精神药物的消费情况以及使用仿制药的意愿和原因。它还评估了仿制药与患者一般特征之间的关联。

设计

在4个月(2021年7月至10月)期间对128名使用精神药物的患者进行了横断面研究。

结果

样本中女性多于男性,平均年龄为38岁。抗抑郁药是消费最多的精神药物,其次是抗焦虑药。近13%的患者通过自我开处方或朋友的建议开始使用精神药物,73.4%的患者使用仿制药。对成瘾的恐惧、品牌药无法获得以及药剂师的建议是报告的使用仿制药的主要原因。

结论

在COVID-19大流行期间,由于新的处方和自我用药,精神药物的消费量增加。与支持实施仿制药处方和替代政策的先前研究相比,使用仿制药与患者特征之间没有差异。

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