Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China; Lanzhou University, an Affiliate of the Cochrane China Network, Lanzhou 730000, China.
School of Public Health, Lanzhou University, Lanzhou 730000, China.
J Clin Epidemiol. 2024 Jun;170:111356. doi: 10.1016/j.jclinepi.2024.111356. Epub 2024 Apr 10.
To investigate the frequency, determinants, stages, and barriers of patient and public involvement (PPI) in systematic reviews and to explore its association with the dissemination of reviews.
We examined systematic reviews that required the inclusion of a PPI declaration, published in The BMJ between January 1, 2015, and December 31, 2022. Multivariable analysis was used to assess the association between PPI and key variables. We investigated the association between PPI and the dissemination of reviews using Altmetric scores, citations, and full-text views.
A total of 217 systematic reviews were included, of which 56 (25.8%, 95% CI 20.0%-31.6%) included PPI, with a steady increase from 5.9% (1/17) in 2015 to 44.4% (4/35) in 2022. Of the 217 systematic reviews, 160 (73.7%) involved methodologists as co-authors. Factors significantly associated with a higher proportion of PPI included the publication year after 2019 (adjusted odds ratio [aOR] 2.46, 95% CI 1.26-4.83), the involvement of methodologist (aOR 3.08; 95% CI 1.27-7.47), and being led by researchers from high-income countries (aOR 5.47; 95% CI 1.23-24.30). Reviews that included PPI had higher Altmetric scores per month (6.6 vs 3.4, P = .002) and more monthly full-text (1048.6 vs 636.5, P < .001) and PDF (217.7 vs 129.0, P < .001) views than reviews without PPI. However, there was no difference in the monthly citations (2.2 vs 2.0, P = .365) between reviews with and without PPI.
The proportion of systematic reviews reporting PPI in The BMJ has increased over time, possibly due to journal policies, but it still remains at a low level. Reviews led by researchers from high-income countries or involving methodologists are associated with a higher frequency of PPI within The BMJ. Furthermore, reviews incorporating PPI within The BMJ have a higher potential for broad dissemination.
调查患者和公众参与（PPI）在系统评价中的频率、决定因素、阶段和障碍，并探讨其与评价传播的关系。
我们检查了需要纳入 PPI 声明的系统评价，这些评价发表在《英国医学杂志》（BMJ）2015 年 1 月 1 日至 2022 年 12 月 31 日期间。使用多变量分析评估 PPI 与关键变量之间的关联。我们使用 Altmetric 分数、引文和全文浏览量来调查 PPI 与评价传播之间的关系。
共纳入 217 项系统评价，其中 56 项（25.8%，95%CI 20.0%-31.6%）纳入了 PPI，自 2015 年的 5.9%（1/17）稳步增加至 2022 年的 44.4%（4/35）。在 217 项系统评价中，有 160 项（73.7%）涉及方法学家作为共同作者。与更高比例的 PPI 显著相关的因素包括 2019 年后的出版年份（调整优势比[aOR]2.46，95%CI 1.26-4.83）、方法学家的参与（aOR 3.08；95%CI 1.27-7.47）和由高收入国家的研究人员领导（aOR 5.47；95%CI 1.23-24.30）。纳入 PPI 的评价具有更高的每月 Altmetric 得分（6.6 比 3.4，P=0.002）和更高的每月全文（1048.6 比 636.5，P<0.001）和 PDF（217.7 比 129.0，P<0.001）浏览量，而没有 PPI 的评价则没有。然而，有 PPI 和没有 PPI 的评价之间的每月引文（2.2 比 2.0，P=0.365）没有差异。
《英国医学杂志》中报告患者和公众参与的系统评价比例随着时间的推移有所增加，这可能是由于期刊政策的原因，但仍处于较低水平。由高收入国家的研究人员领导或涉及方法学家的评价与《英国医学杂志》中更高频率的 PPI 相关。此外，纳入《英国医学杂志》的 PPI 评价具有更高的广泛传播潜力。
