Zhang Y, Ding X, Dai Y
School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China.
National Health Commission Key Laboratory of Parasitic Disease Prevention and Control, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Provincial Medical Key Laboratory, Jiangsu Institute of Parasitic Diseases, Wuxi, Jiangsu 214064, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2023 Dec 1;36(1):91-97. doi: 10.16250/j.32.1374.2023074.
Both parasitic diseases and cancers are disorders that seriously threaten human health. A strong correlation has been recently found between parasitic infections and cancers, and multiple species of parasites and their derived products have shown effective to suppress cancer development, progression and metastasis. Therefore, deciphering the interaction among parasites, cancers and hosts not only provides new insights into the development of cancer therapy, but also provides the basis for screening of parasites-derived active anticancer molecules. This review summarizes the latest advances in the anticancer activity of parasites and underlying mechanisms.
寄生虫病和癌症都是严重威胁人类健康的疾病。最近发现寄生虫感染与癌症之间存在很强的相关性，多种寄生虫及其衍生产品已显示出对抑制癌症发展、进展和转移有效。因此，解读寄生虫、癌症和宿主之间的相互作用不仅为癌症治疗的发展提供了新的见解，也为筛选寄生虫衍生的活性抗癌分子提供了依据。本文综述了寄生虫抗癌活性及其潜在机制的最新进展。
