Department of Human Reproduction, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.
Medical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Int J Mol Sci. 2024 Mar 23;25(7):3613. doi: 10.3390/ijms25073613.
Resveratrol is a polyphenol present in various plant sources. Studies have reported numerous potential health benefits of resveratrol, exhibiting anti-aging, anti-inflammatory, anti-microbial, and anti-carcinogenic activity. Due to the reported effects, resveratrol is also being tested in reproductive disorders, including female infertility. Numerous cellular, animal, and even human studies were performed with a focus on the effect of resveratrol on female infertility. In this review, we reviewed some of its molecular mechanisms of action and summarized animal and human studies regarding resveratrol and female infertility, with a focus on age-related infertility, polycystic ovary syndrome, and endometriosis.
白藜芦醇是一种存在于各种植物源中的多酚。研究报告称，白藜芦醇具有许多潜在的健康益处，具有抗衰老、抗炎、抗微生物和抗癌活性。由于其报道的效果，白藜芦醇也在生殖障碍中进行了测试，包括女性不孕。进行了许多细胞、动物，甚至人类研究，重点是白藜芦醇对女性不孕的影响。在这篇综述中，我们回顾了其一些作用的分子机制，并总结了关于白藜芦醇和女性不孕的动物和人类研究，重点是与年龄相关的不孕、多囊卵巢综合征和子宫内膜异位症。
