Applied Science Cluster (Chemistry), School of Advanced Engineering, UPES, Dehradun 248007, India.
Applied Science Cluster (Chemistry), School of Advanced Engineering, UPES, Dehradun 248007, India.
Food Chem. 2024 Aug 15;449:139204. doi: 10.1016/j.foodchem.2024.139204. Epub 2024 Apr 6.
People with celiac disease or gluten sensitivity may experience an immune reaction to the protein called gluten, which is present in wheat, barley, and rye. A strict gluten-free diet is the sole cure for these ailments. There are chances of food fraud about the claim of being gluten-free food items. As a result, there is a rising need for trustworthy and precise ways to identify gluten. There are many methods to detect gluten in food samples viz., enzyme-linked immunosorbent assay Surface plasmon resonance (SPR), Electrochemical sensors, Fluorescence-based sensors, etc. The use of sensors is one of the most promising methods for gluten detection. For detecting gluten, a variety of sensors, including optical, electrochemical, and biosensors, have been developed with different limits of detection and sensitivity. The present review reports the recent advancements (2019-2023) in the development of sensors for gluten detection in food. We may conclude that sensitivity and limit of detection are not related to the type of sensor used (aptamer or antibody-based), however, there are advancements, with the year, on the simplicity of the material used like paper-based sensors and paradigm shift to reagent free sensors by the spectral analysis. Also, recent work shows the potential of IoT-based studies for gluten detection.
患有乳糜泻或麸质敏感的人可能对称为麸质的蛋白质产生免疫反应,麸质存在于小麦、大麦和黑麦中。严格的无麸质饮食是治疗这些疾病的唯一方法。关于声称无麸质食品的食品欺诈时有发生。因此,需要可靠和精确的方法来识别麸质。有许多方法可以检测食品样品中的麸质,例如酶联免疫吸附试验、表面等离子体共振 (SPR)、电化学传感器、荧光传感器等。传感器的使用是检测麸质的最有前途的方法之一。为了检测麸质,已经开发了各种传感器,包括光学、电化学和生物传感器,它们具有不同的检测限和灵敏度。本综述报告了 2019 年至 2023 年期间用于检测食品中麸质的传感器的最新进展。我们可以得出结论,灵敏度和检测限与使用的传感器类型(适配子或抗体)无关,但是,随着时间的推移,在材料的简单性方面取得了进展,例如基于纸张的传感器,并且通过光谱分析转向无试剂传感器。此外,最近的工作表明基于物联网的研究在检测麸质方面具有潜力。