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三种牙本质过敏症治疗方法的评价:一项随机临床试验。

Evaluation of Three Methods for the Treatment of Dentin Hypersensitivity: A Randomised Clinical Trial.

机构信息

Department of Periodontology, Dental Implants Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Dental Students' Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Int Dent J. 2024 Oct;74(5):1016-1023. doi: 10.1016/j.identj.2024.03.013. Epub 2024 Apr 12.

Abstract

OBJECTIVES

In this study, we aimed to compare the effectiveness of Gluma and high-power 980-nm diode laser, alone or in combination, in the treatment of cervical dentin hypersensitivity.

METHODS

A total of 20 patients (5 men and 15 women), aged 25 to 60 years, who met the inclusion criteria, were enrolled in this study. A total of 60 teeth were randomly divided into 4 groups: G1, 980 nm diode laser (in 2 sessions within a 1-week interval); G2, Gluma (in 2 sessions within a 1-week interval); G3, 980 nm diode laser plus Gluma; and G4: control. Thermal (cold spray) and air blast (air syringe of dental unit) stimuli were used to evaluate cervical dentin hypersensitivity in the patients. Their pain response was assessed using a visual analogue scale (VAS) before treatment (baseline), in the first treatment session (15 minutes after treatment), in the second treatment session (after 1 week), and in 2-week, 1-month, and 3-month follow-up sessions. The obtained data were analysed using non-parametric tests, including Kruskal-Wallis test, Friedman test, Mann-Whitney test, and Wilcoxon test, in SPSS Version 22 at a significance level of P < .05.

RESULTS

Based on the results, there was a significant difference in the average VAS scores for cold and air blast stimuli between the 4 groups 1 month after the intervention (P < .05). Meanwhile, the laser group had the lowest VAS score for cold and air stimuli. On the contrary, no significant difference was found between the 4 groups 3 months after the intervention (P ˃ .05).

CONCLUSION

The present results showed that 980-nm diode laser alone was more effective than the other 2 intervention methods for 1 month.

TRIAL REGISTRATION

The study was registered in the Iranian Registry of Clinical Trials (IRCT20120901010703N5).

摘要

目的

本研究旨在比较单独使用 Gluma 和高功率 980nm 二极管激光,以及联合使用这两种方法,治疗牙本质敏感症的效果。

方法

本研究共纳入了 20 名符合纳入标准的患者(5 名男性,15 名女性),年龄在 25 岁至 60 岁之间。共有 60 颗牙齿被随机分为 4 组:G1 组,980nm 二极管激光(在 1 周内进行 2 次治疗);G2 组,Gluma(在 1 周内进行 2 次治疗);G3 组,980nm 二极管激光联合 Gluma;G4 组,对照组。使用冷喷(冷喷牙科手机)和空气喷(牙科手机的空气注射器)两种刺激物来评估患者的牙本质敏感症。使用视觉模拟评分法(VAS)在治疗前(基线)、第一次治疗后 15 分钟、第二次治疗后 1 周、2 周、1 个月和 3 个月的随访中评估他们的疼痛反应。使用非参数检验(Kruskal-Wallis 检验、Friedman 检验、Mann-Whitney 检验和 Wilcoxon 检验)对获得的数据进行分析,采用 SPSS 22 版进行统计分析,显著性水平为 P<.05。

结果

结果显示,干预后 1 个月时,4 组患者的冷刺激和空气刺激平均 VAS 评分有显著差异(P<.05)。同时,激光组的冷刺激和空气刺激 VAS 评分最低。相反,干预后 3 个月时,4 组之间无显著差异(P>.05)。

结论

本研究结果表明,单独使用 980nm 二极管激光在 1 个月时比其他 2 种干预方法更有效。

试验注册

本研究已在伊朗临床试验注册中心(IRCT20120901010703N5)注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c42/11563163/6f160ba101ef/gr3.jpg

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