细胞外囊泡：mRNA 递送的新途径。
Extracellular vesicles: a new avenue for mRNA delivery.
机构信息
Division of Plant Sciences, School of Life Science, University of Dundee at James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK.
Division of Plant Sciences, School of Life Science, University of Dundee at James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK; Cell and Molecular Sciences, James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK.
出版信息
Trends Plant Sci. 2024 Aug;29(8):845-847. doi: 10.1016/j.tplants.2024.04.001. Epub 2024 Apr 13.
Recent research reveals that plant mRNAs, packaged in extracellular vesicles, are delivered into fungal pathogen cells. Remarkably, the transferred mRNAs are translated by fungal ribosomes, generating functional proteins that impede infection. These findings offer new promising avenues to modify cellular performance by rapid delivery of mRNAs in plant-derived vesicles.
最近的研究表明，植物 mRNAs 被包裹在细胞外囊泡中，并递送到真菌病原体细胞内。值得注意的是，这些被转移的 mRNAs 被真菌核糖体翻译，产生功能性蛋白质，从而阻碍感染。这些发现为通过植物来源的囊泡快速递mRNA 来修饰细胞性能提供了新的有前途的途径。
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