Mahyar Abolfazl, Mahyar Shifteh, Oveisi Sonia, Khajeh Bahman, Khamenehpour Khatereh, Chegini Victoria, Dalirani Reza, Enadi Mojgan, Esmaeili Shiva
Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Pediatric Nephrology Department, Mofid Children's Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Child Neurol. 2024 Spring;18(2):43-53. doi: 10.22037/ijcn.v18i2.43652. Epub 2024 Mar 12.
Shigellosis is one of the common causes of bacterial diarrhea in children. Seizures are common in shigellosis. It is essential to identify the risk factors of seizure in this disease.
MATERIALS & METHODS: This study was conducted on 224 children with shigellosis. The patients were divided into: With (case groups = 63 cases) and without seizures (control group = 161 cases). Groups were compared regarding different variables such as age, gender, clinical symptoms, and laboratory findings. Data analysis was done using statistical tests and SPSS software. Logistic regression analysis was used to determine the risk factors of seizures.
Out of 224 cases of children with shigellosis, 107 (47.8%) were male and 117 (52.2%) female. Significant differences were observed between the two groups in terms of age, history of febrile convulsions, frequency of bloody diarrhea, frequency of fever, duration of diarrhea before hospitalization, abdominal pain, increase in BUN, hyponatremia, hypocalcemia, and red blood cell count in stool (P<0.05). Logistic regression analysis showed that a history of febrile seizure, fever, and hyponatremia are the risk factors for seizures in shigellosis.
This study concluded that a history of febrile seizure, fever, and hyponatremia are risk factors for seizure in childhood shigellosis, thus rapid diagnosis and treatment of childhood shigellosis with risk factors is very important.
志贺菌病是儿童细菌性腹泻的常见病因之一。惊厥在志贺菌病中很常见。识别该疾病中惊厥的危险因素至关重要。
本研究对224例志贺菌病患儿进行。患者分为：有惊厥（病例组 = 63例）和无惊厥（对照组 = 161例）。就年龄、性别、临床症状和实验室检查结果等不同变量对两组进行比较。使用统计检验和SPSS软件进行数据分析。采用逻辑回归分析确定惊厥的危险因素。
在224例志贺菌病患儿中，107例（47.8%）为男性，117例（52.2%）为女性。两组在年龄、热性惊厥病史、血性腹泻频率、发热频率、住院前腹泻持续时间、腹痛、血尿素氮升高、低钠血症、低钙血症和粪便红细胞计数方面存在显著差异（P<0.05）。逻辑回归分析表明，热性惊厥病史、发热和低钠血症是志贺菌病惊厥的危险因素。
本研究得出结论，热性惊厥病史、发热和低钠血症是儿童志贺菌病惊厥的危险因素，因此对有危险因素的儿童志贺菌病进行快速诊断和治疗非常重要。
